The WHO defines Quality of Life (QoL) as a broad concept of 'an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns'. 1 Health-related quality of life (hrQoL) is a more focused, multidimensional concept relevant to a person's health. Definitions differ, but the considered domains usually encompass the 'physical, role functioning, social, and psychological aspects of well-being and functioning'. This includes objective as well as subjective perspectives on all dimensions. 2,3 Alopecia areata (AA) is an autoimmune-mediated disorder characterized by partial or complete non-scarring hair loss whose stigmatizing effect may have a severe psychosocial impact on the affected. The prevalence of AA in children and adolescents is estimated at 1.83% (95% CI: [1.21-2.58]) which is significantly higher than in adults. 4 AA has been shown to be correlated with bullying, poor QoL and psychiatric comorbidities such as clinical depression and anxiety disorders. [5][6][7][8] Whilst the evidence of the effect of AA on QoL in adult patients has been systematically reviewed and found to be detrimental, 6,7,9 to the best of our knowledge until now no summary of the available evidence has been performed in the