Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a type of severe adverse cutaneous drug reaction characterized by fever, skin eruption, hematological abnormalities, and internal organ involvement. Although anticonvulsant drugs are mainly implicated in DRESS, newer anticonvulsants such as oxcarbazepine-induced definite cases of DRESS syndrome are rare and oxcarbazepine-induced DRESS syndrome presenting as exfoliative dermatitis is even rarer. We report a case of a 35-year-old male who developed DRESS syndrome presenting as exfoliative dermatitis after taking oxcarbazepine for 3 weeks.

ABSTRACT:Various skin diseases are seen in pregnancy. Some of these diseases occur specifically in pregnancy. Maternal and fetal morbidity and mortality can be decreased by early diagnosis and appropriate treatment of these conditions. A total of 53 pregnant females were found to have dermatological disorders or sexually transmitted diseases during the study period. The commonest pregnancy specific dermatoses in the study was polymorphic eruption of pregnancy (22.64%) followed by prurigo of pregnancy (9.43%), pruritic folliculitis of pregnancy (5.66%), pruritus gravidarum (0.01%), impetigo herpetiformis (0.01%) and pemphigoid gestationis (0.01%). The commonest dermatological disorder was scabies (13.20%) followed by candidiasis (11.32%), dermatophytosis (9.43%), melasma (5.66%) and equal number of cases of urticaria (3.7%) and acne (3.7%). Among sexually transmitted diseases, commonest disease was genital warts (3.7%) followed by single case (0.01%) each of syphilis, molluscum contagiosum and one patient was seropositive for HIV.

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BACKGROUND: Fixed drug eruption (FDE) is a type of very common cutaneous adverse drug reaction seen in day to day practices. It is very embarrassing to patients due to repeated recurrences and may cause cosmetic problem when present on exposed surface. AIMS: To study the clinical pattern of FDE and identify drugs commonly causing it among patients attending in a tertiary care hospital of southern Assam. MATERIALS AND METHODS: An observational, prospective study was conducted in

BACKGROUNDSystemic Lupus Erythematosus (SLE) is an autoimmune connective tissue disease with multi-organ involvement with skin being the second most commonly affected organ. SLE with skin lesions can produce considerable morbidity resulting from painful skin lesions, oral ulcers, disfigurement or toxic epidermal necrolysis like manifestations, etc. Skin lesions in patients with lupus may be specific (LE specific) or non-specific (LE non-specific) as per the Gilliam classification of skin lesion associated with Lupus Erythematosus (LE). Patients with acute cutaneous LE (Lupus specific) have high chances of having systemic disease.