Polymer lipid nanodiscs have enabled some exciting structural biology and nanobiotechnology applications. The use of a small molecular weight polymer (SMA-EA) has been demonstrated to dramatically increase the size of nanodiscs (upto ~60 nm diameter). Here, we report the first demonstration of the formation of macro-nanodiscs for a variety of lipids, and solid-state NMR experiments utilizing their magnetic-alignement properties.

Retraction of ‘Polymer nanodiscs and macro-nanodiscs of a varying lipid composition’ by Venkata Sudheer Kumar Ramadugu et al., Chem. Commun., 2017, 53, 10824–10826.