Consistent search of plants for green synthesis of silver nanoparticles (SNPs) is an important arena in Nanomedicine. This study focuses on synthesis of SNPs using bioreduction of silver nitrate (AgNO) by aqueous root extract of . The biosynthesis of SNPs was monitored by UV-vis analysis at absorbance maxima 432 nm. The fluorescence emission spectra of SNPs illustrated the broad emission peak 450-483 nm at different excitation wavelengths. The surface characteristics were studied by scanning electron microscope and atomic force microscopy, showed spherical shape of SNPs and dynamic light scattering analysis confirmed the average particle size 32.5 nm and the presence of metallic silver was confirmed by energy dispersive X-ray. Face centred cubic structure with crystal size 33.3 nm was revealed by powder X-ray diffraction. Fourier transform infrared spectroscopy indicated the biomolecules involved in the reduction mainly polyols and phenols present in root extracts were found to be responsible for the synthesis of SNPs. The stability and charge on SNPs were revealed by zeta potential analysis. In addition, on therapeutic forum, the synthesised SNPs elicit antioxidant and antimicrobial activity against, ,, and.

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The entire world is now in a state of caution since the outbreak of a COVID-19 pandemic. The overwhelmingly high spread and mortality rate due to the SARS-CoV-2 virus has not only made headlines but also raised alarming concerns for the human community. Applications of nano-biotechnology along with machine learning have excellent potential in dealing with serious health issues and mainly in medical science. This review article aims to augment the multidimensional use of silver nanoparticles especially in the fabrication of textiles and face masks, which could represent a new avenue for prevention. Further, treatment or disinfection of COVID-19 along with other pathogens using silver nanoparticles and the use of machine learning, which could help in risk assessment.

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