A retrospective analysis of 14 cases of sacral chordoma seen between 1984 and 1993 at the Kidwai Memorial Institute of Oncology is reported. The mean patient age was 54 years, with 13 males and one female. Seventy-one per cent of patients presented with symptoms related to a painful sacral mass. Eight patients underwent radical surgery and two had adjuvant radiotherapy. One patient had a partial tumour resection. Three patients received radical radiotherapy. Two patients were offered only pain relief medication. The median follow-up was 33 months. The actuarial overall survival (OS) at 5 years was 48%. In the 12 patients in whom curative therapy was attempted, the 5-year OS was 56% and progression-free survival was 36%. Four patients developed local recurrence and three developed distant metastasis.

Two cases of chondrosarcoma of the hyoid bone are described. They were managed with surgical resection and postoperative radiotherapy. These patients are disease free at 26 months and 15 months respectively.

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Aim: The objective of this study is the complete elimination of the Keratocystic Odentogenic Tumor (KCOT) along with lining epithelium at the initial operation and induces osteoblastic activity using Concentrated Growth Factor (CGF) derived from autologus blood. Materials: 10 cases were involved in the study; Male: Female ratio 6:4; Maxilla: Mandible ratio 5:5, with a mean age of 36 years. Method: All cases of KCOT were treated by enucleation and chemical cauterization using cornoy's solution followed by placement of CGF in the dead space along with aotogenous bone graft mixed with red blood corpuscular layer. Results: Results were excellent in all the patients with very good ossification at the operated site and none of our patient had recurrence or post-operative complication.. Conclusion: This conservative management of KCOT using cornoy's solution and placement of CGF allows excellent ossification of new bone which in turn useful for future rehabilitation.