Herbal treatments are needed to treat various diseases, one of which is the leaves of Belimbing Wuluh (Averrhoa bilimbi L.). The aim of this study was to formulate chloroform extract of Belimbing Wuluh’s leaf (Averrhoa bilimbi L.) into gel preparations that were good, effective, and safe to use and to determine the antibacterial activity of chloroform extract of Belimbing Wuluh (Averrhoa bilimbi L.) leaf extract to Staphylococcus epidermidis by well method. The results showed that form of gel is a thick, dark green, the distinctive smell of Wuluh starfruit leaf extract, homogeneous, good skin pH, good washing and does not irritate the skin. This study uses Nutrient Agar media as a culture medium for Staphylococcus epidermidis bacteria. The results indicate that the chloroform extract gel leaves of belimbing wuluh leaves in formula 1 (10%), formula 2 (20%), and formula 3 (30%) were able to inhibit the growth of Staphylococcus epidermidis bacteria. In formula 3 (30%) gel extract of belimbing wuluh leaves has the widest zone of inhibition compared to other dosage formulas. The statistical test using the One Way ANOVA test showed a significant difference from the average diameter of the inhibition zone between all concentrations of chloroform extract gel leaves of belimbing wuluh leaves that were significant with (α ˂ 0.05).
Buah Naga Super Merah (Hylocereus costaricensis (F.A.C Weber) Britton & Rose) merupakan salah satu buah yang mengandung antosianin yang dapat dimanfaatkan sebagai antioksidan. Untuk mempermudah penggunaan ekstrak buah naga super merah sebagai antioksidan wajah, ekstrak dibuat dalam bentuk sediaan masker peel-off. Penelitian ini dilakukan untuk mengetahui aktivitas antioksidan ekstrak etanol buah naga super merah dan masker peel-off ekstrak etanol buah naga super merah (Hylocereus costaricensis (F.A.C Weber) Britton & Rose). Ekstraksi dilakukan dengan metode maserasi menggunakan etanol 96% dan diuapkan dengan rotary evaporator hingga didapatkan ekstrak kental. Pengujian aktivitas antioksidan dilakukan secara kuantitatif dengan metode DPPH (1,1-difenil-2 pikrilhidrazil) dan didapatkan nilai IC50 dari masing-masing sampel dengan menggunakan alat spektrofotometer UV-Vis pada panjang gelombang serapan maksimum 516nm. Hasil dari pengukuran didapatkan nilai IC50 masker peel-off ekstrak etanol buah naga sebesar 841,78 ppm. Ini menunjukkan tingkat berpotensi sebagai antioksidan. Dalam penelitian ini, digunakan vitamin C sebagai pembanding. Nilai IC50 vitamin C adalah 1,898 ppm termasuk tingkat antioksidan sangat kuat.
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