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Osteoarthritis (OA) is one of the most common chronic joint diseases and is the leading cause of permanent impairment in patients over 55 years of age. OA's social significance is also determined by their economic weight, which is between 1% and 2.5% of GDP in a number of Western European countries. The main subject of this work is to present the most common degenerative joint diseases and their impact on the quality of life. Material and Methods: Keywords and databases from published literature sources have been used in Scopus, Science Direct, Pub Web, Web of Science, In Cites, Access Medicine over the past 10 years. Results and discussion: OA affects most of the knee, hip and spinal joints, leads to disability and requires costly surgical treatment. The cost of care for OA patients is extremely high due to the need for frequent visits to a doctor, hospitalizations, rehabilitation procedures, expensive treatment and frequent complications resulting from the medication used. X-ray methods are a gold standard in OA diagnosis and the degree of degenerative changes using different scales and estimates depending on the location. OA aggravates quality of life, affecting total physical activity, selfesteem, mental and emotional state of the sick patients. The most commonly used method for assessing the quality of life of patients with osteoarthritis is a matter of SF-36v2, which is based on the norms assessed (NBS). It has been found that 80% of people with OA experience movement difficulties and 25% are unable to cope with their basic daily activities. Conclusion: Degenerative joint diseases are the most common diseases of the musculoskeletal system, which have a significant individual and social effect and significantly impair the quality of life of the patients.

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