Background: Beginning in March 2021, Mexico vaccinated childcare workers with a single-dose CanSino Biologics (Adv5-nCoV) COVID-19 vaccine. Although CanSino is currently approved for use in 10 Latin American, Asian, and European countries, little information is available about its vaccine effectiveness (VE). Methods: We evaluated CanSino VE within a childcare worker cohort that included 1,408 childcare facilities. Participants were followed during March–December 2021 and tested through SARS-CoV-2 RT-PCR or rapid antigen test if they developed any symptom compatible with COVID-19. Vaccination status was obtained through worker registries. VE was calculated as 100% × (1–hazard ratio for SARS-CoV-2 infection in fully vaccinated vs. unvaccinated participants), using an Andersen-Gill model adjusted for age, sex, state, and local viral circulation. Results: The cohort included 43,925 persons who were mostly (96%) female with a median age of 32 years; 37,646 (86%) were vaccinated with CanSino. During March–December 2021, 2,250 (5%) participants had laboratory-confirmed COVID-19, of whom 25 were hospitalized and 6 died. Adjusted VE was 20% (95% CI = 10–29%) against illness, 76% (42–90%) against hospitalization, and 94% (66–99%) against death. VE against illness declined from 48% (95% CI = 33–61) after 14–60 days following full vaccination to 20% (95% CI = 9–31) after 61–120 days. Conclusions: CanSino vaccine was effective at preventing COVID-19 illness and highly effective at preventing hospitalization and death. It will be useful to further evaluate duration of protection and assess the value of booster doses to prevent COVID-19 and severe outcomes.
Objetivo: esta es una investigación cualitativa rápida cuyo objetivo fue analizar las percepciones sobre las prácticas de alimentación de infantes que acuden a guarderías del Instituto Mexicano del Seguro Social (IMSS), en dos entidades federativas de México con prevalencias opuestas de sobrepeso y obesidad. Metodología: se realizaron entrevistas semiestructuradas (n=66) en 14 guarderías del IMSS ubicadas en Oaxaca y Yucatán. Resultados: se encontró que el proceso de alimentación en las guarderías es homogéneo y estructurado. Se percibe en el personal la sensibilización y conocimiento sobre cada parte del proceso para que el servicio de alimentación sea lo más apegado a la normativa. Madres y padres consideran que la alimentación en la guardería difiere de la alimentación en casa. Limitaciones: este estudio no indagó a profundidad sobre prácticas de control alimentario que podrían ejercer padres o cuidadores, y que inciden en la formación de los hábitos. Por último, los resultados y testimonios de este estudio pueden no ser válidos en otros grupos poblacionales. Conclusiones: las guarderías juegan un papel crucial en la formación de los hábitos alimenticios de los menores, al proveer un entorno de prácticas de alimentación saludable y promover el conocimiento de nuevos alimentos.
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