Preeclampsia was identified in 1, 46,320 women or 3.7% of all pregnancies that ended in live births. Berg and colleagues (1996) reported almost 18% of 1450 maternal deaths in United States 1987 to 1990 were complications of pregnancy related hypertension. The syndrome complex of pre-eclampsia and fetal growth restriction have similar pathology of placental insufficiency. Here the blood supply to the fetus is inadequate because of defective placentation which can be part of syndrome of pre-eclampsia or can individually lead to defective growth of the baby i.e. small for gestational age baby. An observational study was done over a period of one year among women attending the out-patient department for antenatal care at Medical College and Hospital. About 52% of women are in the age group 21-30 years and 46% belong to teenage group. Mean gestation age at transvaginal USG is 14+1 and at transabdominal USG is 24+6 weeks.
Background: Post partumhemorrhage (PPH) is an important cause of maternal mortality accounting for nearly 15-20% of maternal deaths in India. Oxytocic drugs like oxytocin, ergot alkaloids, and various prostaglandins are being used for active management of third stage of labour. Materials and Methods: A prospective study was conducted in the Department of Obstetrics and Gynaecology of Al Ameen Medical College, Vijayapur, in 400 women. Patients were randomized into four groups of 100 each and were given oxytocic within 60 seconds of delivery anterior shoulder of the baby. Oxytocics used were 10 IU intramuscular oxytocin,125 µg intramuscular carboprost, 0.2 mg intravenous methylergometrine, and 800 µg tablet misoprostol per rectally in groups A, B, C and D respectively. Results: Duration of third stage of labor recorded was minimum with carboprost with mean duration of 3.84+/-0.99 minutes and was maximum with methylergometrine with mean duration of 5.04+/-1.02 minutes. Amount of blood loss observed was minimum with carboprost (mean 131 +/-72.037 ml) and maximum with Methylergometrine (mean 435+/-147.578 ml). Hemoglobin drop was also seen more with Methylergometrine with mean drop of 0.872+/-0.458 gm% and minimally with carboprost with mean drop of 0.236 +/-0.221 gm%. Conclusion: It is concluded from this study that carboprost is the uterotonic of choice followed by oxytocin for active management of third stage of labor.
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