Tissue engineering has a fundamental role in regenerative medicine. Still today, the major motivation for cardiac regeneration is to design a platform that enables the complete tissue structure and physiological function regeneration of injured myocardium areas. Although tissue engineering approaches have been generally developed for two-dimensional (2D) culture systems, three-dimensional (3D) systems are being spotlighted as the means to mimic better in vivo cellular conditions. This manuscript examines the influence of electrical stimulation on 3D cultures of adipose tissue-derived progenitor cells (ATDPCs). ATDPCs cells were encapsulated into a self-assembling peptide nanoscaffold (RAD16-I) and continuously electro stimulated during 14-20 days with 2-ms pulses of 50mV/cm at a frequency of 1 Hz. Good cellular network formation and construct diameter reduction was observed in electro stimulated samples. Importantly, the process of electro stimulation does not disrupt cell viability or connectivity. As a future outlook, differentiation studies to cardiomyocytes-like cells will be performed analyzing gene profile and protein expression.

Abstract-The human heart tissue has a limited capacity for regeneration. Tissue and cellular therapies based on the use of stem cells may be useful alternatives to limit the size of myocardial infarction. In this paper, the preliminary results from an experimental campaign for on-line monitoring of myocardium scar infarction are presented. This study has been carried out under a research project that has as main objective the development and application of a bioactive patch implant for regeneration of myocardial infarction. Electrical Impedance Spectroscopy (EIS) has been chosen as a tissue state monitoring technique. What is presented in this communication is the first results of an implantable EIS measurement system which has been implanted in a subset of the animals corresponding to the control group, along one month. In all the animals, the myocardial infarction was induced by the ligation of the first circumflex marginal artery. In the animal group presented, the bioactive patch scaffold and the electrodes were implanted without the stem cells load. The scaffold is a piece of decellularized human pericardium, lyophilized and rehydrated with hydrogel RAD16-I. Nanogold particles were also placed near the electrodes to improve the electrode area conductivity. The results presented correspond to the subset of animals (n = 5), which had implanted the bioimpedance system monitoring the electrical impedance spectrum in vivo during 1 month. Two electrodes were connected to the bioactive patch implant. A total of 14 logarithmically spaced frequencies were measured every 5 minutes, from 100 Hz to 200 kHz. Results show a convergence of low-frequency and high frequency impedance magnitudes along the measurement period, which is coherent with the scar formation.

Resumen. Son poco frecuentes los estudios sobre evaluación del bienestar y de la salud de los docentes y esta evaluación requiere incluir las principales afecciones derivadas de los riesgos específicos de la profesión docente así como los principales indicadores de bienestar en la docencia. Por ello, el objetivo del presente estudio es analizar el estado de salud de los docentes de centros concertados en Cataluña. Una muestra de 6208 docentes en activo de centros concertados de Cataluña contestaron el Cuestionario de Salud Docente, cuestionario específico que incluye seis factores: Agotamiento, Afectaciones de la Voz, Afectaciones Músculo-esqueléticas, Afectaciones Cognitivas, Satisfacción y Autoeficacia. Los resultados indican que un 20 % de los docentes tienen una salud baja, siendo las Afectaciones Músculo-esqueléticas y las Afectaciones Cognitivas las que presentan mayor prevalencia, seguidas de Afectaciones de la Voz y Agotamiento. Un 80% de los docentes manifiestan sentirse satisfechos y competentes en su actividad docente. Se observan diferencias en función del género, nivel educativo, edad y años de docencia, siendo los docentes femeninos, de la ESO y con edades comprendidas entre 45 y 55 los que tienen un nivel de salud más bajo. De estos resultados se desprende la necesidad de mejorar las medidas preventivas organizacionales, profesionales y personales. Palabras clave: Profesión docente; condiciones de trabajo del profeso; prevención; satisfacción profesional.[en] Assessment of teachers' wellbeing and work health in subsidised schoolsAbstract. There are not many studies on the assessment of teachers' wellbeing and work health and this assessment needs to include the main conditions derived from the specific risks of the teaching profession, as well as the key indicators of wellbeing in the profession. Therefore, the objective of this study is to analyze the state of health of teachers of state subsidized schools in Catalonia. A sample of 6208 active teachers replied the Teaching Health Questionnaire, a specific questionnaire that includes six factors: Exhaustion, Voice Complaints, Muscle-skeleton Complaints, Cognitive Complaints, Satisfaction and Self-efficacy. The results indicate that 20% of the teachers have a low state of health, being the Muscleskeleton and Cognitive Complaints those with the highest prevalence, followed by Voice Complaints and Exhaustion. 80% of the teachers report feeling satisfied and competent in their teaching. There are differences in gender, educational level, age and years of teaching, being female teachers, teachers working in Secondary Education and aged between 45 and 55 the groups who have a lower level of health. These results show the need to improve organizational, professional and personal preventive measures.