BACKGROUND Most of the thyroid swellings are non-neoplastic and with normal thyroid hormone. So, it doesn't require any surgical excision, even though the thyroid swelling is an indication for surgical excision. The present study was done to evaluate the accuracy of fine needle aspiration cytology (FNAC) for the thyroid swellings and correlate it with the histopathological findings. METHODS This is a prospective study. A total of 47 cases were studied. Fine needle aspiration cytology was done, slides were made and studied. Histopathological examination of the corresponding 47 cases was also done and correlated with FNAC findings. Sensitivity, specificity and accuracy were calculated. RESULTS Age of the patients varied from 20 - 69 yrs. Most of them were in the age group of 30 - 39 years and 50 - 59 years. The ratio of male to female was 1:4.9. Swelling of the neck was the most common presentation in most of the patients. On FNAC 33 (70.2 %) cases were diagnosed as colloid nodular goitre, 04 (8.5 %) as autoimmune thyroiditis, 08 (17.0 %) as follicular neoplasm, 01 (2.1 %) as suspicious of malignancy, 01 (2.1 %) as papillary carcinoma. On histopathological examination 25 (53.2 %) cases were diagnosed as colloid nodular goitre, 01 (2.1 %) as fibrous thyroiditis, 01 (2.1 %) as Graves’ disease, 07 (14.9 %) as Hashimoto’s’ thyroiditis, 06 (12.8 %) as follicular adenoma, 01 (2.1 %) as follicular carcinoma, 04 (8.5 %) as papillary carcinoma and 02 (4.2 %) as NIFTP (noninvasive follicular thyroid neoplasm with papillary like nuclear features). The overall sensitivity was 69.2 %, specificity was 97.0 % and accuracy was 89.3 %. CONCLUSIONS FNAC is a minimally invasive, highly accurate and cost-effective procedure. FNAC helps the clinician to diagnose malignant lesions with confidence. It has high rates of specificity and accuracy but comparatively has less sensitivity. However, it is very important for the management of patients with thyroid swelling. KEYWORDS Fine Needle Aspiration, Prospective Study, Sensitivity, Specificity, Thyroid Swelling

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To study the spectrum and have a clinicopathological correlation of papulosquamous skin lesions. Material and Methods: A series of noninfectious papulosquamous skin lesions coming to Department of Dermatology were studied over a period of one year, i.e. from June 2017 to July 2018. These were correlated and analysed with the histopathological findings. Results: The present study comprised of 70 cases of skin diseases presenting as papulosquamous lesions. Majority of cases were in the age group of 31 to 40 years (16 cases, 22.8%) followed by 11 to 20 years (15 cases, 21.4%). Females were more commonly affected with 37 cases(52.8%) compared to males with 33cases (47.1%) and female to male ratio of incidence being 1:0.89. In the present study, out of 70 cases, 34 cases (48.5%) were diagnosed as psoriasis, Lichen planus-15 cases(21.4%), Chronic Dermatitis-4 cases (5.71%), Lichen striatus-3 cases (4.28%), Pityriasis Lichenoides-2 cases(2.85%), Pityriasis Rosea-2 cases (2.85%), Prurigo Simplex-2 cases(2.8%), Prurigo Nodularis and Lichen Nitidus 1 case each, 1 case each of atopic eczema, contact dermatitis and chronic actinic dermatitis and inconclusive cases being 3. The histopathological findings of psoriasis and lichen planus were studied with special emphasis. The predominant histopathological finding in psoriasis is acanthosis and the predominant histopathological finding in lichen planus was band like infiltrate in the dermoepidermal junction. These findings in addition to other specific findings and clinical correlation were used to give a conclusive diagnosis. There were 4 cases of psoriasis, 2 cases of lichen planus, 2 cases of 1 case of, 1 case of which did not correlate with histopathological findings. Conclusions: In our study females were mostly affected. The age group mainly affected was 31-40 years. Psoriasis was the commonest papulosquamous lesion. Good clinicopathological correlation is very much necessary for diagnosis.