To evaluate the etiology and clinical features of bacterial meningitis (BM) in adults during the period 2015-2018 in Vietnam, a retrospective study was performed at the National Hospital of Tropical Diseases. 102 patients were identified. BM occurred year-round, peaked in July -September, male was 80.4%, over 40 years old accounted for 80.4%. The proportion of patients with underlying diseases was 41.2%, contact with pigs or pork products was 30.4%. Common manifestations were stiff neck, kernig, headache, fever/hypothermia, and altered consciousness.The CSF showed high protein concentration (median 3.2 g/L, range 1.3 -6.2), and leukocytes (median 1312 cell/mm3, range 234-2943). Meningitis associated with septicemia was 29.4%.Streptococcus suis still was the main cause (72.5%), followed by Pneumococcal (6.8%) and a few other causes. Factors associated with the risk of S. suis should be considered were male (OR: