CASEHistory: 72 year old female presented with breathlessness and cough for 4 months .She had history of decreased appetite. She is a known case of Diabetes mellitus and hypertension and is on medication for the same. No family history of similar complaints or chronic illness.Past history of hospitalisation in our hospital 2 months back for similar complaints for two weeks.H/o of intake of Antitubercular medication for last two months4 drugs HRZE (DOTS regime).Physical examination revealed pallor.There was no icterus, cyanosis, clubbing and bony tenderness.Heart rate-90/min,Respiratory rate 32/min.Respiratory distress present.use of accessory muscles of respiration present.Chest examination:Right side of chest appeared prominent. Breath sounds were decreased on right side of chest in mammary, infraaxillary, infrascapular area Bronchial breath sounds and whispering pectoriloquy were present on right mammary area and axilllary area.Systemic examination was normal.On Investigations:Patient had anemia with leucocytosis. Erythrocyte sedimentation rate was raised (64).Liver function tests and Renal function tests were within normal limits.Chest Xray (Fig:1,2)of patient showed consolidation initially which had progressed to pleural effusion in one month. ABSTRACTPulmonary Tuberculosis can co-exist with lung malignancy masking the underlying disorder leading to delay in diagnosis and management. Here we present an interesting case of a 72 year old female who on initial presentation was diagnosed with tuberculosisbut later developed plural effusion during treatment and on investigation was found to have an underlying lung malignancy.Introduction:Pulmonary Tuberculosis and lung carcinoma are the two co morbidities that have been shown in many studies to coexist. Many of Signs and symptoms of Pulmonary Tuberculosis mimics lung carcinoma and coexistence increases mortality and morbidity.So we are presenting a case which had pulmonary Tuberculosis and later developed carcinoma lung.

Introduction: Typhoid fever is highly prevalent in India with hight rate of morbidity and mortality. There is paucity of data from India for its rapid detection by Rapid diagnostic test like Typhidot-M . Thus this study has been taken up to study the use of rapid diagnostic test for typhoid fever keeping blood culture test as gold standard. Materials and Methods : This cross sectional study was carried out in the Department of Pediatrics, Northern Railways Central Hospital, New Delhi. Blood samples of 100 patients with fever of more than 3 days duration were tested by Typhidot-M, Blood culture and S.Widal .S.Widal being done in second week of illness. Other tests for evaluation of other causes of fever were also done.. Results: Sensitivity and Specificity of Typhidot-M was found to be 97.8% and 46.3% .Positive and Negative predictive values for this test were 60.8%and 96.2%.Typhidot-M had better sensitivity and specificity than serum widal test.The association between blood culture positivity and Typhidot-M test was found to be highly significant statistically. Conclusion: We concluded that there was significant association between blood culture positivity and Typhidot -M test in our study thus we can recommend Typhidot -M as the rapid, accurate and reliable tool for the early diagnosis of typhoid fever .