The paper deals with the development of 2-link lower limb extremity manipulator for rehabilitation purposes in bio-medical engineering. The musculoskeletal modeling was performed on the collected human gait data to obtain the joint angles and driving force values for hip and knee movement. The results obtained from the proposed controller were verified using Matlab-Simulink. The robust adaptive RBF neural network and fuzzy sliding mode controller were developed to track the desired trajectory. The OpenSim software was utilized to perform inverse kinematics and inverse dynamics on the musculoskeletal model which is scaled according to the physical dimensions of the experimental subject. The simulation results stated that SMC-RBF network has better tracking rate, less chattering problems and handle unknown uncertainties well. Finally, the results obtained were compared with the existing method with the help of performance index parameters to prove their effectiveness.

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