: HIV patients frequently have mucocutaneous manifestations, which could be the first sign of the infection and can also be prognostic markers for disease progression. This study was done to note the different mucocutaneous manifestations occurring in the people living with HIV/AIDS.: One hundred ensuent HIV seropositive patients who attended the opd were included in the study.: The bulk of the study participants were illiterate, had a mean age of 32, and a male to female ratio of 2:1. The patients' number of manifestations ranged from 01 to 05. The most typical illnesses observed in this investigation were dermatophyte infections followed by oral candidiasis. The most frequent non-infectious symptoms observed in this investigation were SD and PPE. The most prevalent STI was herpes genitalis. Inversely correlated with CD4 level were the type, number, and severity of mucocutaneous symptoms. The number of manifestations and CD4 count were found to be inversely correlated. The majority of PLHAs (55%) exhibited several manifestations. The majority of the manifestations are unusual, persistent, recurrent, and resistant to the therapy. Young patients presenting with extensive SD, PPE, OC, scrofuloderma, and HZ should encourage the clinician to investigate the patient's sero-reactivity status
BACKGROUND Erythema multiforme is an acute self-limited syndrome with distinctive skin lesions, with or without mucosal lesions, which can be precipitated by various agents. EM minor denotes mild cutaneous syndrome. EM major denotes more severe syndrome, with marked mucosal involvement. METHODS 50 clinically diagnosed cases of erythema multiforme attending DVL department, attached to GGH Kurnool, were studied. A detailed proforma was taken, which included 1). Detailed history including chief complaints related to skin. 2). Complete physical and systemic examination. 3). Relevant investigations were done. RESULTS In the present study, 50 clinically diagnosed cases of erythema multiforme were enrolled. 31-50 yrs. (40%) age group patients showed peak incidence, with slight female preponderance. Incidence of EM minor (84%) was much higher than EM major (16%). Systemic drugs are the main cause for EM minor (50%) and the sole cause for EM major. Among drugs, Sulphonamides (20%) are the commonest cause. Next come Infections (30%) among which Herpes simplex (20%) is most common; followed by Radiotherapy. All cases of EM major showed symmetrical involvement, bullous lesions, erosions over both skin and mucous membranes. EM minor presented with papular lesions, 'Target' lesions over extremities. CONCLUSIONS The present study emphasises that EM can be diagnosed clinically. Drugs are the sole cause for EM Major.
BACKGROUND Alopecia areata is an immunologically mediated disorder characterized by focal to diffuse hair loss. AA is hypothesized to be an organ specific autoimmune disease mediated by T lymphocytes directed against the hair follicles. Although genetic predisposition and environmental factors may trigger the initiation of the disease, the exact cause is still unknown. METHODS 100 clinically diagnosed cases of Alopecia Areata attending DVL department, attached to GGH Kurnool, were studied. A detailed proforma was taken, which included-1) Detailed history including chief complaints related to skin and hair. 2) Complete physical and systemic examination. 3) Relevant investigations were done in patients. A prospective, descriptive study on Alopecia Areata subjects was conducted over a period of 22 months from December 2014 to September 2016, attending the OutPatient Department of DVL, Government General Hospital attached to Kurnool Medical College, Kurnool. RESULTS In the present study the incidence of alopecia areata in patients attending DVL outpatient department is 1.9. CONCLUSIONS In the study period of 22 months, percentage of AA cases observed is 1.9% among all cases attending DVL OPD, GGH, Kurnool. Among study subjects, most common age group affected is 20-40 years. In this study, systemic disorders associated with AA are atopy (12%), thyroid abnormalities (11%), diabetes mellitus (5%), hypertension (2%), dental caries (7%), iron deficiency anaemia (6%), down's syndrome (1%), right maxillary sinusitis (1%), jaundice (1%) and CSOM (1%).
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