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Essential oils (EOs) and their individual components have several biological properties and are used in cosmetics, food and pharmaceutical industries. However, their application still presents a challenge owing mainly to their volatility and their poor aqueous solubility and stability. The aim of this study was to evaluate, for the first time, the ability of Captisol® (sulfobutylether-β-cyclodextrin, SBE-β-CD) and Captisol-G® (sulfobutylether-γ-cyclodextrin, SBE-γ-CD) to encapsulate the main volatile components of six essential oils (EOs), to enhance the aqueous solubility of these EOs and to generate controlled release systems. The performance of these CDs was compared to hydroxypropyl-β-cyclodextrin (HP-β-CD) and γ-cyclodextrin (γ-CD), respectively. The most common native CDs are α-, β-and γ-CDs and are made up of six, seven and eight glucosyl units, respectively (Figure 1).Incorporating EOs as inclusion complexes in cosmetic, food or pharmaceutical formulations present several advantages. CDs might enhance the solubility of EOs and their components thus higher concentrations could be used, 8,9 produce easy measurable dosage forms, facilitate their dispersion and protect them from interactions --------------------------------------------------------------------------------------------------------------------------------This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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