Durable control of human immunodeficiency virus (HIV) replication and lack of disease progression in the absence of antiretroviral therapy were studied in a military cohort of 4586 subjects. We examined groups of elite controllers (ie, subjects with plasma HIV RNA levels of <50 copies/mL; prevalence, 0.55% [95% confidence interval {CI}, 0.35%-0.80%]), viremic controllers (ie, subjects with plasma HIV RNA levels of 50-2000 copies/mL; prevalence, 3.34% [95% CI, 2.83%-3.91%]), and subjects with a lack of disease progression (ie, long-term nonprogressors [LTNPs]) through 7 years of follow-up (LTNP7s; prevalence, 3.32% [95% CI, 2.70%-4.01%]) or 10 years of follow-up (LTNP10s; prevalence, 2.04% [95% CI, 1.52%-2.68%]). For elite and viremic controllers, spontaneous virologic control was established early and was typically observed when the initial viral load measurement was obtained within 1 year of estimated seroconversion. Elite controllers had favorable time to development of AIDS (P=.048), a CD4 cell count of 350 cells/microL (P= .009), and more-stable CD4 cell trends, compared with viremic controllers. LTNPs defined by 10-year versus 7-year criteria had a longer survival time (P=.001), even after adjustment for differing periods of invulnerability (P= .042). Definitions of controllers and LTNPs describe distinct populations whose differing clinical outcomes improve with the stringency of criteria, underscoring the need for comparability between study populations.

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A successful transformation of the energy and transportation sector is one of the main targets for our society today. Battery electric vehicles can play a key role in future renewable-based energy supply systems because of their ability to store electrical power. Additionally, they provide significant charging flexibility due to the long parking durations. In this paper, we provide insights into the temporal and power-specific flexibility behavior of three different vehicle fleets. These fleets are pool vehicles of office employees, a public authority, and a logistics company. Several parameters, such as the average charging power per charging event or the average plug-in duration per charging event, are discussed. Additionally, we investigate different charging rates and their impact on the temporal flexibility of the charging events. The data analysis shows that the logistics site has the most homogeneous charging profile as well as high charging flexibility, in contrast to the office and public agency site. The results are of significant importance for future applications in the field of smart charging and ancillary services provision.