Background Periampullary carcinoma includes a group of malignant neoplasm arising in the pancreas or in or near the ampulla of vater. Main modalities of treatment in patients with obstructive jaundice due to periampullary carcinoma: resection of the tumor with bilioenteric anastomosis, palliative surgical bypass and stent insertion. Aims and objectives To nd out results, morbidity and mortality to various modalities of treatment to all operable and non operable case of obstructive jaundice due to periampullary carcinoma following proper diagnosis by clinical, radiological and other investigation procedures Materials and methods This is a prospective study on patients presented with obstructive jaundice due to periampullary carcinoma with special reference to its management, admitted in different surgical units of Nootan Medical College & Research Centre, Visnagar from the month of August 2019 to July 2022 suspected due to peri-ampullary carcinoma. Results and discussion Twenty eight cases studied in regard to their incidence of age, sex, religion, occupation, their clinical features, investigations different etiological factors of obstructive jaundice due to periampullary carcinoma and their management. Maximum numbers of obstructive jaundice due to periampullary carcinoma were found to be due to carcinoma head of pancreas, Most of the patients present late and curative resection was not possible in them 24 out of 30 patients were operated out of which 10 had denitive surgery and in 14 palliative surgeries were done. Conclusions Most of the patients' present late and curative resection was not possible in them. Surgical palliation is a better alternative in those patients when nonsurgical palliation is not available