O objetivo do presente estudo foi quantificar o tipo físico ideal e verificar o nível de insatisfação com a imagem corporal de praticantes de caminhada. Participaram do estudo 186 pessoas: 87 mulheres (idade = 28,70 ± 12,6 anos, estatura = 161,6 ± 6,2cm, massa corporal = 58,9 ± 12,0kg e gordura = 25,7 ± 7,8 G%) e 98 homens (idade = 27,9 ± 12,9 anos, estatura = 177,2 ± 6,9cm, massa corporal = 75,0 ± 12,3kg e gordura = 13,3 ± 6,1 G%). Solicitou-se que as pessoas indicassem qual silhueta correspondia ao seu corpo atualmente e qual gostariam de atingir. Apenas 24% das mulheres estão satisfeitas. A silhueta 3 foi apontada como ideal a ser atingido por 55% das mulheres (silhueta 2 = 18%; e 4 = 21%). A silhueta 3, de acordo com os resultados desse estudo, corresponde ao G% 20,5 ± 0,9% (EPM) e ao IMC de 20,0 ± 0,3kg/m² (EPM). Quanto aos homens, apenas 18% estão satisfeitos. A silhueta 4 foi apontada como ideal por 47% dos homens (silhueta 3 = 23%; e 5 = 19%). A silhueta 4 corresponde ao G% 9,8 ± 1,4% (EPM) e ao IMC de 23,1 ± 0,4kg/m² (EPM). Existe um tipo físico ideal para ambos os sexos. Não houve diferença entre o grau de insatisfação com a imagem corporal entre os sexos.

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Natural products are continually explored in the development of new bioactive compounds with industrial applications, attracting the attention of scientific research efforts due to their pharmacophore-like structures, pharmacokinetic properties, and unique chemical space. The systematic search for natural sources to obtain valuable molecules to develop products with commercial value and industrial purposes remains the most challenging task in bioprospecting. Virtual screening strategies have innovated the discovery of novel bioactive molecules assessing in silico large compound libraries, favoring the analysis of their chemical space, pharmacodynamics, and their pharmacokinetic properties, thus leading to the reduction of financial efforts, infrastructure, and time involved in the process of discovering new chemical entities. Herein, we discuss the computational approaches and methods developed to explore the chemo-structural diversity of natural products, focusing on the main paradigms involved in the discovery and screening of bioactive compounds from natural sources, placing particular emphasis on artificial intelligence, cheminformatics methods, and big data analyses.

Introduction: Currently, good appearance is a synonym to success, health and determination. So as to, the modern society overwhelms the individuals to follow beauty stereotypes. The heritage of this capitalist and selfish society is the psychological appearance disorders and the psychological dependence associated with them. Among these, we can mention vigorexy and exercise dependence. Objectives: I) to compare vigorexy levels and exercise dependence among gym goers and bodybuilders, II) to correlate the variables on physical practice (time of practice, weekly frequency and sessions time) to the frequency dimensions of vigorexy and exercise dependence; and, III) to compare vigorexy levels according to the exercise dependence groups (dependent or in risk, not symptomatic dependent and not asymptomatic dependent). Methods: The sample was composed of 151 male gym goers (27.66 ± 6.54-year-old and 27.56 ± 5.03 BMI) and 25 bodybuilders (30.80 ± 5.54-year-old and 26.72 ± 4.24 BMI). The participants answered the Exercise Dependence Scale and the Muscle Dysmorphia Disorder Inventory. The statistical analysis involved descriptive, univariated normality, comparative and correlational analyses. results: The main results were: I) absence of differences between gym goers and bodybuilders concerning vigorexy levels and exercise dependence, II) training session time is positively correlated with most of the dimensions of the exercise dependence, and, III) the group classified as dependent or in risk reveals medium superior levels of vigorexy. Conclusion: lastly, it was found that both in bodybuilders and gym goers, the higher the vigorexy level, the higher the exercise dependence with this correlation in bodybuilders.