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Fifty-nine students who had previously taken degrees or commenced careers in subjects other than medicine entered the Cambridge Clinical Course in its first 5 years of operation, commencing in 1976. A questionnaire was used to ascertain their original career plans when entering medical education, their career plans in 1981, and the reasons for any changes. Graduates originally planning careers in general practice and teaching or research maintained their intentions, but some of those who had favoured hospital clinical work changed their minds in favour of general practice. General practice was also the most common choice amongst those students who were earlier unsure as to what branch of medicine they would enter. Of students changing their career intentions, half indicated that disenchantment with hospital medicine was a prime reason for the change.