Fish pedicures and/or fish manicures are treatments performed in spas involving the use of the living fish <i>Garra rufa</i>. In the last decade, the use of <i>G. rufa</i> for cosmetic and therapeutic reasons has become increasingly popular. The patients are placed into a bath to control psoriasis, eczema, or other skin conditions, but there is no scientific proof of their effectiveness. Most of the infections described in association with fish spas result from minor skin injury and contact with fish carrying such bacteria as <i>Staphylococcus aureus</i>, <i>Aeromonas sobria</i>, and <i>Mycobacterium marinum.</i> Therefore, fish spas in general should not be recommended, particularly for diabetic patients, immunocompromised patients, or patients treated with biological agents.