Background
Long‐term follow‐ups after receiving lycopene therapy for management of oral submucous fibrosis (OSMF) are scarce. The study aimed to assess the long‐term efficacy of lycopene for management of OSMF symptoms.
Methods
In this prospective clinical study, 400 clinically diagnosed early OSMF patients were assessed for the efficacy of lycopene in alleviation of burning sensation (BS) and reduced mouth opening (MO) symptoms in comparison to placebo. After 1‐year follow‐up, group A (lycopene group) was divided equally into group A1 and group A2. group A1 patients were retreated with lycopene and the A2 group was followed without retreatment. After 2‐year follow‐up, the Group A2 patients were advised retreatment but not followed as most of the patient did not agree for follow‐up. However, group A1 patients were continued to follow‐up every 6 months for a total three years. Statistical analysis was by independent sample t‐test and P‐value <.05 were considered as significant.
Results
A statistically significant difference (P < .05) in BS and MO was found between group A and B with lycopene showing better results. At one‐year follow‐up, a statistically significant recurrence in the symptoms was found (P < .05) in the lycopene group (group A). After the second intervention, there was a statistically significant difference in the improvement of symptoms between the group A1 and A2 at 6 months and 1 year (P < .05) with group A1 (retreatment) showing better results.
Conclusions
Treatment with lycopene led to improvement in the symptoms of OSMF in the present study. The results highlight the importance of retreatment of lycopene for its long‐term effect on alleviation the symptoms of OSMF.
Objective
The steady and continued increase of the Journal of Oral Pathology & Medicine's (JOPM) popularity prompted a bibliometric analysis of the journal. The purpose was to assess the significance and effect of the published research articles in the Journal from 1972 and 2020, aiding the identification of landmark articles. We performed a bibliometric analysis using the top 100 cited papers in the Journal of Oral Pathology & Medicine.
Materials and Methods
An extensive review of the Web of Science was undertaken. Standard information such as author details, affiliated institutions, publication year and the country of origin was recorded.
Results
The top 100 cited articles in JOPM were assessed. The maximum and minimum number of citations in the top 100 articles was 1459 and 95, respectively. A total of 16 790 citations were recorded for these 100 articles. Authors were affiliated to 28 different countries, 17 research articles from the UK and 12 from the USA. Other countries furnished seven or fewer articles.
Conclusion
This bibliometric analysis provides a synopsis of research published in the journal over a 48‐year period. Recent interest in the journal shows a healthy increase in submissions and profile.
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