Background: Dutasteride has been found to reduce chronic prostatic bleeding and when taken 2 -6 weeks preoperatively reduces bleeding during transurethral prostate resection. The aim of this study is to determine if the drug will be effective in the control of acute gross prostatic haematuria. Patients and Method: 87 Consecutive patients with gross haematuria were enrolled. Clotting Profile, Cystoscopy and Intravenous Urography were done to exclude haematuria from medical, renal and bladder causes. Patients suspected to have prostatic haematuria were further evaluated using serum Prostate specific antigen (PSA) and Prostate scan. Those with elevated PSA ≥ 10 ng/ml and abnormal digital rectal examination (DRE) finding had prostate biopsy. The patients were randomly divided into 2 treatment groups. The control group had Normal saline irrigation and broad spectrum antibiotics while the second group received 0.5 mg oral dutasteride in addition. The time taken and volume of irrigation fluid used before haematuria stopped were noted. Statistical analysis was done using SPSS version 20.0. Result: 75 patients had haematuria of prostatic origin. 49 (65.3%) of these had benign prostatic hyperplasia (BPH) and 26 (34.7%) had cancer of prostate. 25(51%) of the 49 patients with BPH had Normal saline irrigation and antibiotics while 24 (49%) had oral dutasteride in addition. 14 (53.8%) of the prostate cancer patients had Normal saline irrigation and antibiotics while 12 (46.2%) had dutasteride in addition. Haematuria resolved in significantly shorter length of time using lesser volume of irrigation fluid in those treated with dutasteride than in those on control arm. Conclusion: Addition of 0.5 mg oral dutasteride daily leads to early resolution of acute prostatic haematuria.

Background: Surgical haematuria is not very common but ominous when it occurs. Knowledge of the causes will help in the adequate management of the disease. Aim: To evaluate the causes of surgical haematuria in Port Harcourt, Nigeria. Materials and Method: This is 10 years retrospective study of patients who presented at the University of Port Harcourt Teaching Hospital and 4 other private urology centres in Port Harcourt with haematuria of surgical aetiology between January 2012 and December 2021. Their history, examination findings and investigations were evaluated. Patients with medical haematuria and incomplete records were excluded from the study. Results: Three hundred and forty-six patients were evaluated. The mean age was 58.12 ± 5.1. Two hundred and sixty-four (76.3%) were men and eighty-two (23.7%) were females. The three commonest causes of haematuria were Benign prostatic enlargement, prostate cancer and urolithiasis with a frequency of 126 (36.41%), 66 (19.08%) and 40 (11.56%) respectively. The cause of haematuria was benign in 232 (67.06%) subjects and malignant in 114 (32.94%). Conclusion: The commonest causes of haematuria are of prostatic origin, mainly benign although malignancy is a significant cause.

Introduction: Malignant renal tumours (MRTs) pose significant morbidity and mortality. In adults, renal cell carcinoma (RCC) constitutes about 90% of these tumours whereas in children, the majority are nephroblastomas. Males are generally more affected than females. Nuclear grade, tumour stage, size and histopathological subtype are prognostic factors. In our environment, patients with MRTs commonly present late. Methods: Clinical and demographic details of patients who had malignant tumours diagnosed on renal biopsy tissue between 2002 and 2013 at the

Purpose: Haematuria is a very important sign and symptom of a urological disease. It may be due to a urological malignancy. Careful history, physical examination, investigation and monitoring is necessary to identify cause and adequately treat patient with haematuria. This study aims to highlight the management of haematuria in Port Harcourt, Nigeria. Methodology: This was a retrospective study of patients who presented with visible haematuria between January 2012 and December 2021. The patients' history, physical examination findings, investigations and treatment received were analysed. The form of treatment received was noted. Findings: Three hundred and forty-six patients were evaluated. Two hundred and fifty-six (74%), seventy-two (20.8%) and eighteen (5.2%) patients presented within a week, between two and three weeks and above 3 weeks respectively. Twenty-seven (7.81%) patients had emergency surgery for haematuria. Sixteen of these had prostatectomy, 3 had TURBT/ chemotherapy, and eight had nephrectomy. The others were managed conservatively. Unique contribution to theory, practice and policy: Many patients with surgical haematuria present early. The commonest cause of haematuria is benign prostatic enlargement and the commonest emergency surgery is open prostatectomy. Haematuria is mainly managed conservatively. Careful monitoring of patients' vital signs is critical in identifying patients who begin to decompensate during conservative treatment. When the need arises, immediate surgical intervention should be carried out.

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