BackgroundSickle cell disease (SCD) is the most prevalent monogenic hereditary pathology associated with the presence of hemoglobin SS in the world. It can affect individuals, leading to changes in the face and body, causing a deficiency in dental and bone tissue formation that can ultimately result in a higher level of predisposition to developing dental caries. This study aimed to evaluate the oral condition of children and adolescents with SCD in comparison with the condition of healthy controls.MethodsThis was a cross-sectional study of children and adolescents aged 5 to 18 of both sexes from a hematology center in Bahia, Brazil, and subjects without hemoglobinopathies from a public school of the same state (comparison group). There were 124 individuals, 63 in the comparison group and 61 in the disease group. Interviews, dental and periodontal exams using the DMFT and Periodontal Community Index, respectively, were performed, and the salivary buffer capacity and salivary flow rates of the entire sample population were evaluated. The categorical variables were compared using a chi-square test or Fisher’s exact test. For comparison of means, the Student’s-t test was used for independent samples that presented symmetrical distribution.ResultsThe study showed that the DMFT was 2.08 (2.71) for the SCD group and 1.05 (1.67) for the comparison group (p = 0.013). For dmft, the values were 2.3 (2.6) and 0.88 (1.2), respectively, (p = 0.018). Exams of the periodontium showed the presence of gingival bleeding and dental calculus, with no statistical significance between groups (p = 0.984). When evaluating salivary flow and buffer capacity, no significant differences were observed for the flow rates (p = 0.485), but the SCD group presented a lower buffer capacity compared with the comparison group (p = 0.006). Individuals who used hydroxyurea had a dmft (2.50) higher than that of the comparison group (2.00), and salivary flow was lower than the normal rate in 70% of the children who did not use this medication.ConclusionChildren and teenagers with SCD had deficient oral health when compared with the comparison group, presenting a higher level of dental caries and lower buffer capacity.

Simultaneous irradiation of multiple flasks may have deleterious effects on the polymerization of microwave cured-acrylic resins. This study evaluated the effect of the number and position of flasks in the monomer release, Knoop hardness and porosity of a microwave-cured acrylic resin. Samples were made of Acron MC(R) (AMC, GC Dent. Ind. Corp.) processed at 500 W. The following associations of the number and position of the flasks were tested: one simple flask centrally placed on the turning plate (I, control); two flasks, one in the centre (IIa) and the other peripherally placed in the plate (IIb); two flasks centrally, one above (IIIa) and the other below (IIIb). The processing time varied according to the number of flasks: 3 or 4.5 min for one or two flasks, respectively. For monomer release, each specimen (n = 12) was put in an assay glass tube containing 6 mL of deionized water that was changed daily. Monomer levels were obtained by spectrophotometry at 206 nm. For hardness test (n = 10), 12 indentations were made in the surface of each specimen. Immersing the polished specimens in permanent ink and counting the porous in a stereo light microscope verified the porosity. Monomer release was significant before 24 h: GI = 263.1(153.3)a, GIIa = 236.9(180.2)a, GIIb = 441.5(446.2)a, GIIIa = 1216.6(857.9)b. Tukey test showed no statistically significant differences among the groups for porosity and hardness. Monomer release was affected by the position of the flask (P < 0.05).

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Within of the limitations of this study, the data suggested that the denture adhesive tested did not significantly alter the oral microbiota during the 14-day trial period.

Oral condition, habits and treatment necessity of institutionalized elders in Araras (SP, Brazil) (p= 28,7). This population requires special care focused on the oral health because besides having a high DMF-T, they also present inadequate oral health self-knowledge.