O vírus Zika é um arbovírus emergente e, desde a sua confirmação no nordeste do Brasil, em maio de 2015, dispersou-se rapidamente para quase todos os países da América Latina e do Caribe. A maioria das pessoas infectadas com o vírus Zika são assintomáticas; no entanto, em mulheres grávidas, a infecção pode causar graves complicações para o feto. Na investigação de 60 grávidas com exantema e com média de idade gestacional de 20 semanas, houve confirmação laboratorial para o vírus Zika (biologia molecular e/ou sorologia) e, até o momento, sem coinfecção e nenhum registro de alterações ultrassonográficas ou desfechos com microcefalia ou outra malformação.
Objective. To establish the risk of microcephaly in neonates born to women infected with ZIKV during pregnancy. Methods. A cohort of laboratory-confirmed ZIKV cases of congenital infections (109 mothers infected during pregnancy and 101 newborns) among 308 suspect cases was followed in Belem, Pará, Brazil, from October 2015 to December 2017. Results. A microcephaly risk of 1.98% (95% CI 0.54-6.93%) was found, or 2 cases among the 101 neonates infected with ZIKV during pregnancy. 72% of the pregnant women had ZIKV infection confirmed by RT-qPCR during gestation. Conclusions. Results showed a low incidence of ZIKV-associated birth defects, stillbirth, and miscarriage, which contrasts with previous studies in other Brazilian regions. Previous exposure to yellow fever vaccine and/ or multiserotype DENV infection could be implicated in the protection from ZIKV congenital infection.
A endometriose é uma doença ginecológica caracterizada pelo implante anômalo de tecido endometrial em localização extrauterina, pode comprometer órgãos e estruturas pélvicas e à distância. Estima-se prevalência da doença de 5 -20% na população feminina, sendo clinicamente marcada por dor, infertilidade, disquezia, constipação e tenesmo, o que pode influenciar na qualidade de vida dos pacientes. Tradicionalmente, o tratamento medicamentoso é a primeira opção para a endometriose. No entanto, existem circunstâncias em que a intervenção cirúrgica é necessária, preferida ou solicitada. Perante isso, objetivamos revisar e compilar os conhecimentos atuais sobre o tratamento cirúrgico da endometriose pélvica. Para isso, utilizou-se as bases de dados PubMed e SciELO, com "cirurgia", "videolaparoscopia" e
Background: The aim of this study was to analyze the demographic, ethyological and clinical aspects of patients with liver cirrhosis treated in the Chronic Liver Disease Center.
Methods: a descriptive, cross-sectional and retrospective study based on the analysis of 580 pacients’ medical records with the diagnosis of hepatic cirrhosis treated from 2004 to 2014 in Belém, Brazil.
Conclusions: the profile was predominantly of male patients, aged between 51 and 60 years, coming from the capital Belem, whose main etiologies of cirrhosis were C hepatitis and alcohol. Ascites was the most frequent clinical manifestation and Child-Pugh score A was the most prevalent.
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