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SummaryIncubation of fibrinogen with small amounts of thrombin resulted in the occurrence of soluble fibrin monomer complexes. These complexes consisted predominantly of a derivative with a higher molecular weight than that of fibrinogen. It was characterized by its relative electrophoretic mobility in 5% PAA gel (0.28 × 10-5 cm2/V × sec) and its elution position prior to the fibrinogen peak following gel filtration. Using adsorption chromatography on insolubilized fibrinogen the derivative dissociated at a ratio of almost 1 : 1 into one part which was adsorbed and into fibrinogen which was not adsorbed. The part which was adsorbed seemed to be the thrombin mediated fibrin monomer. This study confirms the concept that dissociable dimeric fibrinogen-fibrin monomer complexes occur after limited action of thrombin on fibrinogen.

The effects of gynaecological operations on the well-being and satisfaction of patients can be viewed as important supplements to quality assurance which is mainly based on clinical parameters and medical ratings. In the present study 215 patients undergoing gynaecological operations assessed different components of their subjective health status at times of admission to the hospital, at discharge and six weeks after discharge. Additionally, the patients gave satisfaction ratings at discharge. The study resulted in demonstrating considerable improvements of complaints and well-being that continued into the postdischarge period. The improvements were most pronounced in the cases of patients with vaginal hysterectomy. Satisfaction with the hospital department was high, especially with regard to the care given by the physicians and the nurses. After mastectomy, women expressed problems with their self-image and with their partners. Considerations to take the results of the study into account for quality assurance are discussed.

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Septic ovarian vein thrombosis is commonly the sequela of puerperal purulent endomyometritis. The incidence has been reported to be 1 in 600-6000 deliveries. The predominant location is the right ovarian vein according to the puerperal uterine drainage. The diagnostic and therapeutic experience in 9 cases is described. The leading symptoms were abdominal pain localized at the psoatic muscle and a tender, barrel-shaped tumor. Ultrasound and computed tomography (CT) added in the correct preoperative diagnosis. Antibiotic therapy and anticoagulation are recommended in an uneventful course; in complicated cases surgical intervention becomes mandatory.