No abstract

This study is essentially an extension of the work of cm2) and the power measuring .-quipment. The method Daily, et al. [1, 21 and Richard, et al. [3], who demonstrated that of measurement and calibration data are described in 12.3-cm radiation could produce lens opacities in the eyes of animals. Because of the broader implication of their findings in terms of greater detail elsewhere [4]. human analogy, this present investigation was designed to gain some idea of what microwave power densities should be considered dan-DO& AVN gerous for human exposure. Both wavelength and power densities used for this purpose are of interest in the applied fields of microwave diathermy, radar communications, and microwave research. _ i cpoloc c:eolsJovel INSTRUMENTATION M DLECTOR T HE SOURCE of high-frequency radiatioIn (12.3 CmP | fis TC H0J3i#J: wavelength) was the Raytheon Microtherm-director C, Model CDM4.1 This instrument is rated at about 01I-CMe "c" RNTEAWN 100 watts of conitinuous wave power output, and pro9YrNEH4E M'C*TItC)sEJM duces a microwave beam of previously undefined density. MODL Z>M + The Microtherm is approved by the American Medical Association for use in diathermy and operates at a freo.e o quency of 2,450 megacycles per second as authorized by r O the Federal Communications Commission. -Io H -I3 -a e r . Power output of the Microtherm was measured by ta.r Io I 50J, aI I0 03 means of a Hewlett-Packard Microwave Power Meter, -T_ 2 0.0 101 iiI I t1e Ta Model 430B, employed in conjunction with a Hewlett-+1 Packard tunable bolometer, Mount Model 475B, and a 2 , 7-7A section of attenuation cable RG-21/4 (55.00 decibels). Fig. 1-Power distribution in beam at 2-and 3-inch distances from C the of the Raytheon Microtherm at 100 per cent power output (95 w). same equipment except that 26.34 db of attenuation were used between a dipole pickup antenna (effective area-21.3 Beam power densities at the 2-and 3-inch exposure position are shown in Fig. 1. The power density in each * This work was accomplished at the Radiobiology Laboratory, square inch of the 3 X 4-inch cross section is shown to Atomic Warfare Directorate, AF Cambridge Res. Center, Air Res. the nearest tenth of a watt/cm2. Calibration of the beam and Dev. Command, Cambridge, Mass. This report is a condensed version of the complete study (in press); A.M.A. Archives of Oph-oppossite the dipole crossover at these and other distances t.halmology and Schlool of Aviation Medicine, USAF, Rep. No. shownl in Fig. 2 enabled an estimate to be made of the t Dept. of Radiobiology, School of Aviation Mledicine, USAF, previously unknown powver densities which had been Randolph Field, Tex. employed in other studies. For example, Daily et at. [2] t St. John's Hospital, Lisle Street, Leicester Square, London, woke at 2-t.-nhpstos prxmtn .3t W.C. 2, Eng.wokda2-t -nhpstosapomalg0.3o § Biophysics Division, AF Special WAeapons Center, Kirtland AF 0.16 wratt/cm2, while Richardson et atl. [3] used about 'Obtained on loan from the Raytheon MIfg. Co., W\altham, Mtass. 0.5 to 0.6 watt...

No abstract

SummaryThe concentrations of 5-hydroxytryptamine (SHT), noradrenaline, and dopamine were estimated post mortem in brain stem, hypothalamus, and caudate nucleus in 33 patients who had been treated with isocarboxazid, clorgyline, or tranylcypromine and 11 controls. Similar and highly significant increases in SHT and noradrenaline concentration occurred with all three drugs. The distribution was unimodal, but about a quarter of the patients showed only a small increase in brain amines. Tranylcypromine seemed to have a significantly greater effect on dopamine in caudate nucleus and hypothalamus compared with isocarboxazid and clorgyline. In the doses used chlorpromazine did not reduce the amine concentrations. Four patients with Parkinson's syndrome had low concentrations of dopamine in caudate nucleus in spite of monoamine oxidase inhibitor administration.