The title compound, [Ni(C6H8N2)3]Cl2.2(H2O), was synthesized by slow evaporation method at room temperature. The structural study by X-ray diffraction indicate that this compound crystallize in the triclinic system, P-1 space group with a=10.222(2) Å, b=10.757(2) Å, c=11.441(3) Å, α=114.30(4)°, β=99.43(3)° and γ=93.01(3)°. The structure is formed by the cation [Ni(C6H8N2)3] 2+ , tow chloride anions and two molecules water of crystallization. The nickel (II) atom is coordinated to six nitrogen donors from three neutral 2-AMP ligands, adopting a slightly distorted octahedral geometry. The crystal structure is stabilized by strong hydrogen bonds of N-H…Cl, O-H…Cl, C-H…Cl and π-π interactions to obtained three-dimensional network. The newly prepared compound was characterized by XRD, Infrared, UV-Vis spectroscopy and Hirshfeld surface (3D-HS) analysis. Vibrational analysis of the compound was realized by infrared spectroscopy. The optical properties of the crystal were studied using optical absorption UVvisible spectroscopy which confirmed the semiconducting properties by revealing a direct optical band. Hirshfeld Surface projections and Fingerprint plots were elucidated the relative contribution of the H…Cl, C…H, C…C, C...N, H…O intermolecular contacts in the crystal.