SummaryDrugs with antidopaminergic properties and those capable of stimulating serotonin release can be responsible for hyperthermia syndromes such as neuroleptic malignant syndrome and serotonin syndrome. Dopamine and serotonin are important neurotransmitters in temperature regulation and it is likely that these reactions result from drug-induced changes in neurotransmitter levels. We describe three cases of drug-induced hyperthermia, discuss their aetiology and management, with both general measures and therapies designed to redress neurotransmitter imbalance.
SUMMARYFew doctors working in the accident and emergency (A&E) department will have had experience in the management of adder (Vipera Berus) bites. While such events are uncommon, and rarely fatal, prompt correct management undoubtedly helps in reducing mortality and morbidity. Various isolated case reports (Watson
Cystic fibrosis (CF) is an autosomal recessive condition affecting one in 2,000 live births in the UK. There are few reports of malignant tumours in this condition probably because, until recently, the majority died before the age of 30 years as a result of recurrent and chronic bronchopulmonary infection with impaired growth and development and resistance to infection due to pancreatic malabsorption. We describe an adult male with CF who died from an adenocarcinoma affecting the ileocaecal region of the bowel.
We present certain characteristics of 1,000 consecutive patients who attended an Accident and Emergency Department (A&E) with an injury sustained as a result of sport. The majority of injuries occurred as a result of football. Sports injuries had a higher requirement of X-ray than general trauma patients. A minority were treated at the site of injury. A fifth of patients required no treatment or a simple dressing. Commonest treatment was a support bandage. Only 2% required immediate in-patient treatment. Those affected by sports injuries tend to be young and of working age and may lose work time as a result of their injuries and therefore appropriate treatment is justified.
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