Abstract. West African Dwarf (WAD) goat plays an important socio-economic role, hence the effect of 82 days of feeding Gmelina leaf meal (GLM) diets on feed intake, body weight change and blood indices of WAD goats were investigated. A total of 36 WAD goats averaging 9.04 kg in weight were randomly divided into four groups of nine goats each with three goats constituting a replicate. The groups were randomly assigned four experimental diets (T1, T2, T3, and T4, containing GLM at 0%, 12%, 24% and 36%, respectively) in a completely randomized design. Results indicated significant (p<0.05) improvement for body weights and feed conversion ratio for T2, T3, and T4. There was significant difference (p<0.05) for all the haematological parameters except packed cell volume (PCV). White blood cells (WBC) increased in their number (p<0.05) with incremental levels of GLM in the diets. All the serum biochemical indices showed significant (p<0.05) difference with glucose and cholesterol concentration reduced (p<0.05) with incremental levels of GLM. It could be concluded that GLM can be included in the diets of goats up to 36% without deleterious effects on the productive and physiological indices of WAD goats.