Objective: To compare the effectiveness and safety of carbetocin, misoprostol and syntocinon in reducing the amount of blood loss following cesarean deliveries. Patients and Methods: This randomized study was carried out on 180 attended for delivery. A double-blind randomized controlled trial enrolled patients with a singleton pregnancy scheduled for an elective cesarean delivery. The primary outcome was the amount of blood loss. The secondary outcome was the occurrence of uterine atony necessitating additional uterotonics. Per-protocol analyses were performed. Patients, investigators and data analysts were masked to treatment assignments. Results: It was found that the carbetocin group showed a significant decrease in blood loss intra and post-operative. Also, the decrease in both Hb and Hct level was significantly lower than the other two drugs. On the other hand, the complication and side effect of carbetocin were significantly lower than the other two drugs. Conclusion: Additional uterotonics were needed less frequently by patients treated with carbetocin. Carbetocin was superior to syntocinon and misoprostol in reducing the blood loss and preventing uterine atony following an elective cesarean delivery.

Background: Intra cytoplasmic sperm injection (ICSI) is one of the effective treatments in women with fertility problems; however, there are no approved predictors for pregnancy till the present moment. We aimed to evaluate the role of progesterone and endometrium pattern in predicting pregnancy in ICSI cycles. Patients and Methods: The study included 200 women who were treated in Al-Shatby Hospital in (ICSI) Unit from January 2017 to October 2018. They underwent one super ovulation protocol which was gonadotrophin in which releasing hormone progesterone was measured in the 14 th day; while ultrasound was performed in the 3rd day and in the day of HCG administration. Results and Conclusion: Progesterone with a cutoff point of 27 ng/mol is a significant predictor of pregnancy in ICSI cycle. However, neither endometrial thickness nor pattern was a significant predictor of pregnancy.