A painless inguinal or scrotal tumor is a characteristic of the uncommon illness known as liposarcoma of the spermatic cord (LSC). We introduce a 40-year-old man who was hospitalized to the Surgery Department with indications of a right inguinal unilateral, painless, hard, firm mass that was slow-growing. Histopathology evaluation revealed a lipomatous neoplasm formed of lobules of fat cells of variable size having large nuclei with few showing nuclear indentation by vacules. The fat cells are separated by either loose myxoid stroma or fibrous stroma that shows atypical cells with large hyperchromatic nuclei. The mass is surrounded by an intact facia. The submitted membranes and fibrofatty tissues are free from tumor invasion.

Background: α-Amylase enzyme is digestive enzyme that breaks down complex carbohydrates like starch into simpler sugars; it is being studied as a potential target for anti-cancer therapies. Objective: The current study aimed to evaluate the general characterization, and inhibition of α-Amylase enzyme, which had been purified from the sera of patients diagnosed with Breast Carcinoma. Materials and methods: A total of 100 blood serum samples were collected from patients with Breast cancer from Baghdad National Hope Hospital in Baghdad. α-Amylase enzyme was purified from serum clinical isolate in three stages; precipitation with 65% saturated ammonium sulphate, ion exchange chromatography utilizing a DEAEcellulose column, and gel filtration chromatography with a sephadex G-200 column. Changing conditions in pH, temperature, inhibitor concentration, and kinetics all affect the activity of the α-Amylase enzyme. Results: α-Amylase inhibition assay showed that Vitis vinifera L. was the most potent inhibitor (71.8%). During the kinetic investigation of the enzyme, it was discovered that the inhibitory mechanism that the extracts use is noncompetitive. Vmax was 0.023, and 0.012 mmol min -l at 75 μg/ml of Vitis vinifera L. , Verbena Officinalis L .extracts, respectively. Conclusions: High specific activity for α-Amylase purified from sera of Iraqi breast cancer patients was obtained after three purification steps. Ethanolic plant extracts showed inhibitory effect on α-Amylase while Vitis vinifera L. was the most potent inhibitor.

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Background: Globally, healthcare authorities have reacted by restricting medical care to emergency cases and postponing elective surgical procedures of all types. Elective surgeries have been almost totally postponed keeping to a minimum the risk of transmission of SARS-CoV-2 and to allow a better allocation of resources. Since thyroid surgery usually does not cover immediate surgical interventions, during this pandemic nearly all the patients who require thyroid surgery care are experiencing delays in the operation planning procedure. Objective: The aim of the work was to investigate the impact of COVID-19 pandemic on thyroid surgery. Subjects and methods: We conducted prospective study from August 2020 to February 2021 among all patients who attended to Damanhur Medical National Institute Hospital. Total sample size was 60 patients and patients with positive COVID-19 were enrolled in group 1 (cases) and those who were negative COVID-19 were enrolled in group 2 (controls). Results: A total of 60 patients were seen during the study period. Males were 35 (58.3%) while females were 25 (41.7%). The mean age 39.5± 9.5 years. There is no statistically significant difference between patients with COVID-19 and patients without COVID-19 regarding developing complications from thyroid surgeries. Conclusion:The COVID-19 pandemic has created a complicated set of issues for patients with endocrine-related cancers. Most thyroid cancers are indolent and so postponement of surgery in the era of COVID-19. There is no significant association between COVID-19 and complications of surgery.