D iabetes mellitus (DM) is one of the most serious diseases that affect human health; DM is predicted to be the seventh leading cause of death by 2030 in the world. Diabetes particularly Type 2 is characterized by persistent production of reactive oxygen species (ROS) and generation of oxidative stress. Natural antioxidants have shown improving in treatment of diabetes. Therefore, this study was conducted to investigate the antioxidant activity of beetroot powder (BP) in different concentrations on alloxan -induced diabetic rats. Thirty adult male albino rats weighting (160±10) were divided into 5 equal groups of 6 animals each, one was kept as a control -Ve group, while the other 4 groups were treated with alloxan (150 mg/kg body weight) to induce diabetes mellitus. Group (2) were left as a control +Ve (diabetic rats) fed on normal diet at all experiment period (28 days), group 3,4 and 5 diabetic rats treated with 2%, 4% and 8% of beetroot powder, respectively. Liver enzymes activities, lipid profiles, antioxidant enzymes and glucose level in serum were examined. Significant increased in antioxidant enzymes activities of groups treated with beetroot powder in different concentrations. Treatment with BP with different concentration resulted in decreasing the rise of mean serum liver enzymes activities and prevented the rise of mean glucose concentrations in diabetic groups. On conclusion, the present study demonstrated the daily consumption of beetroot powder with meals could be potentially useful in improving hyperglycemia and diabetic complications.increasing the level of antioxidant activity. Therefore, these findings recommended BP to be included in our daily diets, drinks and food supplementation. ReferencesAbdul Bari, M.A.; Albadri, M.H. and Hussein, F.H. (2018): The protective effects of beetroot against Dexamethasone induced damage in liver, kidney and Hyper-lipidemic effects in mice .Wipmr., 4(11):60-68. ADA, American Diabetes Association (2004): Diagnosis and classification ofdiabetes. Diabetes Care 27 (1):5-10. Allain, C. C; Richmond, N. and Rosechloy, P. (1974): Cholestrol enzymatic colorimetric test. Chem. Clin., 19 (20): 1350 -1361. Beals, W.J.; Binns, E.S.; Davis, L.J.; Giordano, R.G.;Klochak, L.A.; Paris, L.H.; Schweder, M.M.; Peltonen, L.G.; Scalzo, L.R. and Bell, C. (2017):Concurrent beet juice and carbohydrate ingestion influence on glucose tolerance in obese and non-obese adults. Journal of Nutrition and Metabolism, 2017:1-7. Chhikara, N.; Kushwaha, K.; Sharma, P.; Gat, Y. and Panghal, A. (2019): Bioactive compounds of beetroot and utilization in food processing industry: A critical review, Food Chemistry Journal, 272:192-200. Clifford, T.; Howatson, G.; West, J.D. and Stevenson, J.E. (2015): The potential benefits of red beetroot supplementation in health and disease. Nutrients, 7: 2801-2822. Coles, L.M. and Clifton, P.M. (2012): Effect of beetroot juice on lowering blood pressure in free-living, disease free adults: arandomized, Placebo-controlled trial. ‫النوعية‬ ‫التربية‬ ‫كلية‬ -‫المنيا‬ ...

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D ill and fennel seeds are herbal plants cultivated in various regions worldwide; they have many therapeutic effects such as anti-inflammatory, antibacterial, antiviral, anti-hyperlipidemia and antidiabetic. Therefore, this study was conducted to examine the effect of fennel and dill seeds powder on serum lipid profile of rats feeding high fat diet. Forty adult male albino rats weighting (200 ±7g) were divided into eight equal groups of 5 animals each, one was kept as a control (-Ve) group, while the other 7 groups were fed on high fat diet (HFD), group (2) were left as a control (+Ve) fed on HFD only all experiment period (28 days), groups (3,4) fed on HFD+ 2.5% and 5% of dill seeds, respectively, while groups (5,6) fed on HFD+ 2.5% and 5% of fennel seeds, respectively, the last groups (7,8) fed on dill and fennel seeds mix (50/50 w/w) with 2.5% and 5%, respectively. At the end of experiment serum glucose level, liver enzymes activities, kidney functions and lipid profile were examined. The results indicated that the increase of fennel seeds or dill seeds concentration resulted in reduction of serum glucose level and significant (p≤0.05) decreased serum very low-density lipoprotein (VLDL), low density lipoprotein (LDL), triglyceride and cholesterol. Also, the results revealed that fennel seeds have a better effect than dill seeds on high density lipoprotein (HDL) level. Treatment with fennel seeds or dill seeds at different levels caused significant (p≤0.05) decreased uric acid, creatinine and urea levels compared to positive control group. The results also revealed there no significant differences between the groups in albumin level. There was a significant (p≤0.05) decrease in the activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) of fennel seeds and dill seeds groups compared to positive control group. Therefore, the present study concluded that fennel and dill seeds powder could be used into daily foods and beverages as hypo-lipidemic herbs.