It is possible to replace the inner bark of the adult tree for the stems and leaves from the shoots as raw material to be used in the preparation of its the phytotherapeutics. Therefore, this finding may help in the implementation of public policies that ensure the conservation of the species along with its sustainable use for pharmaceutical purposes.
Background
Stroke necessitates interventions to rehabilitate individuals with disabilities, and the application of functional electrical stimulation therapy (FEST) has demonstrated potential in this regard.
Methods
We performed a systematic review according to the recommendations of the PRISMA checklist, searching MEDLINE, Cochrane, EMBASE, LILACS, and PEDro databases by July 2022, without any date or language limitations. Studies were selected using the following terms: stroke, electrical stimulation therapy, cycling, and clinical trials. Randomized or quasi-randomized clinical trials were included that investigated the effect and effectiveness of FEST combined with exercise programs and FEST alone for motor function and activity in subacute post-stroke individuals. The quality of included trials was assessed using the PEDro scores. Outcome data were extracted from eligible studies and combined in random-effects meta-analyses. The quality of evidence was determined according to the Grading of Recommendations Assessment, Development, and Evaluation system.
Results
Five randomized clinical trials involving 187 participants were included. Moderate-quality evidence indicates that FEST combined with exercise programs promotes relevant benefits in trunk control (MD 9 points, 95% CI 0.36 to 17.64) and walking distance (MD 94.84 meters, 95% CI 39.63 to 150.05, I = 0%), the other outcomes had similar benefits. FEST compared with exercise programs promotes similar benefits in motor function and activity.
Conclusion
This systematic review provides low to moderate-quality evidence that FEST combined with exercise programs provides similar or superior benefits in motor function and activity in early subacute post-stroke individuals.
Review registration: PROSPERO (CRD42022345282)
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