The flow distribution in manifolds is highly dependent on inlet pressure, configuration, and total inlet flow to the manifold. The flow from a manifold has many applications and in various fields of engineering such as civil, mechanical, and chemical engineering. In this study, physical and numerical models were employed to study the uniformity of the flow distribution from manifold with various configurations. The physical model consists of main manifold with uniform longitudinal section having diameter of 10.16 cm (4 in), five laterals with diameter of 5.08 cm (2 in), and spacing of 22 cm. Different inlet flows were tested and the values of these flows are 500, 750, and 1000 L/min. A manifold with tapered longitudinal section having inlet diameters of 10.16 cm (4 in) and dead end diameter of 5.08 cm (2 in) with the same above later specifications and flow rates was tested for its uniformity too. The percentage of absolute mean deviation for manifold with uniform diameter was found to be 34% while its value for the manifold with nonuniform diameter was found to be 14%. This result confirms the efficiency of the nonuniform distribution of fluids.