No abstract

SRT boost is more effective in reverting the poor prognostic influence of local persistent disease.

In a specific group of patients with CRN of the temporal lobe in whom the CRN lesions were causing a mass-occupying effect beyond the temporal lobe, excision of the contrast-enhancing region was safe and could achieve prompt resolution of brain edema and a low incidence of recurrence of CRN.

Objective:To report our local experience on incidence and outcomes of different paediatric brain tumour. Methods: A detailed data search was carried out from our operative records and histopathology database. A total of 48 paediatric patients bearing 49 brain tumours (one patient had two tumours) within the period between 1992 and 2001 was retrieved. The discharge summary, out-patient follow-up record was examined for each patient. The data was grouped according to different pathology type. Results: The results were mainly concentrating over several selected pathologies: (i) low-grade glioma; (ii) high-grade glioma; (iii) germ cell tumour; (iv) medulloblastoma; and (v) craniopharyngioma. Conclusions:The most prevalent pathology in our experience is low-grade astrocytoma, followed by germ cell cell tumour and medulloblatoma. The highest mortality rate is high-grade glioma.

Hereditary haemorrhagic telangiectasia (HHT), or Osler-Weber-Rendu syndrome, is an autosomal dominant condition characterized by recurrent epistaxis, multiple telangiectasia and visceral vascular malformations. Brain abscess is a common presentation secondary to pulmonary arteriovenous malformation (AVM) in HHT patients. The prevalence of HHT in the Chinese population is not known, and is not commonly report. Here, we report on a Chinese patient who suffered from HHT and presented with multiple brain abscesses and a renal abscess. Upon further investigation of the patient's medical history and a physical examination, it was found that he had recurrent epistaxis and telangiectasia over his tongue, as well as fingers. Subsequent examination found pulmonary and hepatic AVM. He had a fair recovery after treatment of brain abscesses and pulmonary AVM. We believe HHT is underreported in the Chinese population. Simple history taking and physical examination in patients with a brain abscess can aid diagnosis and prevent complications with prophylactic treatment.