Background: The aim was to evaluate the antifungal activity of propolis extract against Candida albicans (or C. albicans) in patients with vulvovaginal candidiasis. Methods: The research presents a quantitative approach with an experimental design, with a population of C. albicans strains isolated from patients diagnosed with vulvovaginal candidiasis who were admitted to the Gynecology Service of the Maria del Socorro Clinic, district of Ate, Lima; a sample of 34 strains was chosen in total, considering three repetitions per strain, obtaining 102 experimental units. The antifungal susceptibility test was carried out by the disc diffusion plate method using a single concentration of propolis extract, with fluconazole as a positive control. Results: Propolis extract was shown to inhibit all strains of C. albicans, as was fluconazole, with the effect of the latter being significantly greater than that of the product under investigation. Conclusions: The conclusion is that propolis extract does show antifungal activity against C. albicans in patients with vulvovaginal candidiasis.

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Background: The erythrocyte sedimentation rate (ESR) is used for diagnosis in inflammatory processes, including during the coronavirus disease 2019 (COVID-19) pandemic affecting our population. To determine the values of ESR in the evolution of patients with COVID-19 undergoing treatment at the CLAS Health Center in Nuevo Lurín. Methods: Our research applied a quantitative-observational, descriptive, and longitudinal approach. The sample consisted of 26 male and 19 female patients treated at the study site between February and June 2021, none of whom were in critical condition. To collect all the necessary information, the Capillary or Wintrobe method was used to determine the values of ESR in the evolution of the COVID-19 patients, obtaining different values for the 45 patients seen at the study site. The normal ESR value was 0 - 15mm/h for males and 0 - 20mm/h for females.  Results: The initial ESR test in patients positive for COVID-19 showed that only two cases (0.04%) had slightly elevated ESR ranges, while in the rest of the values (95.56%) remained within the normal range. Conclusions:  From the results of the capillary velocity of sedimentation method, it can be concluded that patients with COVID-19 in Peru showed no signs of inflammation within their bodies due to the virus.

Background: The implementation of electronic taxation systems helps every company to be able to control, verify and simplify its tax operations. It allows them to manage all their obligations in a faster and more efficient way. In this study, we aim to deduce from the accountants' perspective, what attitudes, practices and compliance with tax obligations are being carried out as a result of the implementation of electronic invoicing. Likewise, to note the benefits it has brought to Micro and Small Enterprises during COVID-19 in Peru. Methods: We used methods of applied research with a quantitative and non-experimental approach. The sample consisted of 384 accountants who manage taxation in their respective companies in Metropolitan Lima, to whom a questionnaire was applied as a data collection instrument. Results: The study sample believes that the use of an electronic issuance system can help combat tax evasion (9.6%), cumbersome tax audits (38.8%), informality (9.4%), falsification of payment vouchers (8.9%), loss and deterioration of payment vouchers (9.1%) and informality (8.3%). They also consider, in their opinion, that the use of the electronic tax system has greatly facilitated the taxation processes (96.6%), generated a reduction in costs (96.4%), reduced the use or consumption of paper (96.9%) and streamlined the administrative and accounting operations (97.4%) of the MSEs Conclusions: It is evident that the sample is in favour of the implementation with an electronic tax system in their business. This new system would be a promising means to help businesses voluntarily comply with their tax obligations. In turn, it generates a positive effect on tax collection and compliance levels.