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Citation: Rachuonyo HO, Gatheri GW, Ogola PE, Arika WM, Wambani JR, et al. (2016) In vitro Antifungal activity of leaf extracts from Aloe secundiflora, Bulbine frutescens, Vernonia lasiopus and Tagetes minuta against Candida albicans. Med Aromat Plants 5: 229.

Benign prostatic hyperplasia (BPH) is an age dependent condition that affects old men. The condition is associated with symptoms like frequency in urination, hesistancy, nocturia, weak urine stream and sexual dysfunction. There is thus, need for update of the medications of the disease. Most BPH patients use conventional methods that include drugs targeting 5-alpha reductase enzyme and invasive surgery. These conventional methods lead to severe side effects including erectile dysfunction and gynecomastia. People prefer to go for phytotherapy for the management of the condition to avoid these adverse effects. Finasteride, for example has been found to cause erectile disfunction unlike Serenoa repens whose side effects are infrequent and mild. This review provides information on conventional methods of alleviating the condition as well as phytotherapy options. Alternative medicine alleviate the symptoms of BPH but have less severe or no side effects.

Background: Immune abnormalities are occasioned during HIV infection consequently predisposing opportunistic infections. In part, these derangements result from impaired expression of a number of immunologically important cytokines. However, exact mechanisms behind HIV infectivity on immune system maturation and cytokine production is not well elucidated, more specifically during treatment with HAART. As such, this review compiles data from various studies with the aim of understanding alterations in cytokine network during the course of HIV infection, while assessing the impact of antiretroviral treatment towards cytokine expression.

The main aim of the study was to test for the antimicrobial potency of Aloe secundiflora, Bulbine frutescens, Tagetes minuta and Vernonia lasiopus against Staphylococcus aureus. All the plants showed a pronounced antimicrobial activity against Staphylococcus aureus with Tagetes minuta being the most active at low concentrations (MIC 8.9 mg/ml; MBC 10.0 mg/ml) whereas Vernonia lasiopus showing less activity (MIC 12.2 mg/ml; MBC 14.2 mg/ml). The efficacy test was carried out using the disc diffusion method. The standard antibiotics used were ciprofloxacin (5 µg/ml) and vancomycin (3 µg/ml) showed significant antimicrobial activity by producing zones of inhibition of 22 mm and 25 mm respectively. Dimethyl sulphoxide and distilled water were used as negative control. The extracts from the plants were also screened for the presence of phytochemicals with the results showing the presence of flavonoids, alkaloids, tannins and saponins in all the extracts. The study suggested that the selected medicinal plants can be used effectively in the treatment of bacterial infection caused by Staphylococcus aureus.