The road adhesion coefficient is a key factor influencing automatic emergency braking (AEB) and anti-lock braking system (ABS) safety control of trucks. With the fading factor introduced, and the covariance gain adjusted in real time, the strong tracking unscented Kalman filter (STUKF) algorithm is modified to estimate the road adhesion coefficient more accurately. Composed of an ABS fuzzy sliding mode controller (SMC) and an AEB controller, an AEB/ABS coordinated control strategy with an adhesion coefficient estimation is designed for a three-axle heavy vehicle. The control effects are verified through experiments on various road conditions based on a hardware-in-loop test platform. The test results show that the proposed control strategy has a better braking efficiency than the traditional AEB/ABS and AEB control strategy without adhesion coefficient estimation and can decrease braking distance by 8.4% and braking time by 5.9%, which is beneficial to the vehicle longitudinal safety.