BackgroundDepressive symptoms are a pervasive mental health problem in Chinese adolescents. The aim of this article was to systematically assess the trend of depressive symptoms in China among adolescents (1988 to 2018).Material/MethodsA systematic and comprehensive literature search was conducted in both English and Chinese databases, including PubMed, EMBASE, Cochrane CENTRAL, CNKI, and Wan Fang Database, to identify relevant studies published between 1988 and 2018. Batteries of analyses in this meta-analysis were undertaken using Stata version 12.0 statistical software.ResultsSixty-two related reports involving 232 586 participants finally met our inclusion and exclusion criteria. The results suggest the prevalence of depressive symptoms has generally increased over time. The prevalence estimates before 2000 were 18.4% (95% CI, 14.5–22.3%), and were 26.3% (95% CI, 21.9–30.8%) after 2016. The pooled prevalence of depressive symptoms among children and adolescents was 22.2% (95% CI: 19.9–24.6%, I2=99.6%, p<0.001). More subgroup analyses classified by screening instrument, gender, and region were carried out in this meta-analysis.ConclusionsResults of our meta-analysis suggest that depressive symptoms have become more prevalent among Chinese adolescents. This trend emphasizes the need for effective prevention strategies and greater availability of screening tools for this vulnerable population.

Aim To determine the prevalence of dementia in the past two decades and provide updated estimates about older people (aged ≥60 years) with dementia in China from 2015 to 2050. Methods The English and Chinese databases were retrieved. Published epidemiology surveys of dementia from 1990–2018 were screened. Meta‐analysis was used to calculate their pooled prevalence. The age‐moving method was used to estimate the population aged ≥60 years in 2020, 2030, 2040 and 2050 based on the data of the sampling survey of 1% of the population in 2015 released by the National Bureau of Statistics. The pooled prevalence of three age groups (60–69, 70–79, ≥80 years) from 2015 to 2018 was used as the basis to estimate the number of older people with dementia. Results The pooled prevalence rate of dementia in Mainland China from 1985 to 2018 was 4.9% (95% CI 4.3–5.4), and the prevalence rate from 2015 to 2018 among them was 7.4% (95% CI 5.3–9.5). In 2020, 2030, 2040 and 2050, the number of people with dementia will be 16.93 million, 24.25 million, 31.98 million and 35.98 million, respectively. Furthermore, people with dementia aged ≥60 years in 2050 will be 2.13‐fold than that of 2015. Conclusion The number of dementia patients in China will increase dramatically in the next 30 years without preventive measures. Geriatr Gerontol Int 2019; 19: 1096–1100.

The existence of depression among children or adolescents can trigger a sequence of burdens on themselves, their families and even the whole society, which cause both physical and economic impacts. Our network meta-analysis (NMA) was aimed at comparing them with each other for evaluating the optimal psychosocial therapy to help children and adolescents with depression to improve their mental health. Based on several biomedical databases, a system of search strategies was conducted for searching randomized controlled trials (RCTs) which published from their inception on October, 1st 2018 without language restriction. We carried out an expression analysis for comparing the efficacy of various psychosocial therapies using Bayesian NMA. A battery of analyses and assessments, such as conventional meta-analysis and risk of bias, were performed concurrently. Only 32 of RCTs which involved 2677 participants were eventually included in our analyses from the 19,176 of initial citation screening. In addition, in terms of various valid assessment instruments, interpersonal psychotherapy [standard mean difference (SMD) = −1.38, Credible interval (CrI) − 2.5, − 0.20)], computer cognitive-behavioral therapy (SMD = −1.36, CrI − 2.59, − 0.14), cognitive-behavioral therapy (SMD = −1.16, CrI − 2.15, − 0.18), had significantly better effects than the named control group. All together, these results suggest that interpersonal psychotherapy might be the best approach to improve the depressive state among children and adolescents. This study may provide an excellent resource for future endeavors to utilize psychosocial interventions and may also serve as a springboard for creative undertakings as yet unknown. Keywords Psychosocial therapies • Children and adolescents • Depression • Bayesian network meta-analysisJing-hong Liang and Jing Li have contributed equally to the work presented here and, therefore, should be considered equivalent authors.

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