The results of treatment by Cryosurgery of 52 patients with cervical erosions and chronic cervicitis were compared with those obtained in 50 patients treated by diathermy cauterization. The extent of the diseased area in all the patients was such that electrocautery in the Out-patient Department would have been inadequate. The refrigerant used for cryosurgical treatment was nitrous oxide delivered through a special cervical probe. A single treatment with cryosurgery resulted in an 83 per cent rate of complete healing compared to a 62 per cent rate of complete healing after diathermy cauterization. This difference was statistically significant. (P = 0.02).

Summary In twenty patients, Stage I endometrial carcinoma was diagnosed by curettage and treated with gestonorone caproate given systemically, prior to hysterectomy. The histological appearances of the tumours before and after treatment were compared and were related to the total dose of progestogen given. In general, regression of the tumour was noted together with increase in differentiation, particularly of tumours initially showing some degree of differentiation. The future of progestogens in the treatment of endometrial carcinoma is discussed.