Background: Literary works about the role of rival convention in relationship with oxidative pressure are opposing and there is no reasonable agreement in distributed ripeness articles about the role of opponent reproduction convention with this respect. In reality, a few creators support the presence of expanded oxidative initiated oocyte harm in ladies experiencing ART's; regardless, others have denied such a perception. Hence, the present investigation was arranged so as to think about the conceivable oxidative or hostile to oxidative potential controlled by foe convention. Aim of the study: The aim of the current study was to evaluate the serum and follicular ROS concentration in women undergoing ICSI contrasted between two groups, one receiving conventional antagonist protocol and the other receiving conventional agonist protocol. Patients and Methods: The current case control study included two groups of subfertile women. The study group included 57 women receiving antagonist protocol, whereas, the control group included 10 subfertile women receiving agonist protocol. The study was carried out at High Institute of Infertility Diagnosis and Assisted Reproductive Technologies at Al- Nahrain University. The study started on April 2018 and extended to March 2019. Women in both groups were subjected to ICSI procedure according to procedures and techniques adopted in High Institute of Infertility Diagnosis and Assisted Reproductive Technologies at Al- Nahrain University with a single basic difference concerning the ovarian stimulation protocol. Results: Overall clinical pregnancy rate was 44.7 % being significantly higher in antagonist group in comparison with agonist group 50.9 % versus 10.01 %, respectively (P = 0.019). There was no significant difference in the concentration of ROS at cycle day 2 between antagonist and agonistgroups (P = 0.561). There was highly significant difference in the serum concentration of ROS at day of ova pickup between antagonist and agonist groups (P = 0.009); being less in antagonistgroup and there was highly significant difference in the follicular fluid concentration of ROS between antagonist and agonist groups (P = 0.003); being less in antagonist group. Conclusions: Antagonist protocol is associated with significantly higher positive pregnancy outcome in comparison with agonist protocol because of the anti-oxidant effect attributed to antagonist use.

Oxidative stress in the field of reproduction has been extensively considered in association with sperm properties and male infertility; in any case, the effect of oxidative stress in association with oocyte trademark got less thought than that of sperms. The goal of the study is to understand the possible association among serum and follicular oxidative markers in infertile women and oocyte characteristics and pregnancy result in ICSI cycles. The present case-control study included 57 infertile women undergoing ICSI that was done in the High Institute of Infertility Diagnosis and Assisted Reproductive Technologies at Al- Nahrain University. The assessment started in April 2018 and connected with March 2019. Mean metaphase II oocyte count of all women was 5.70±3.87, that of pregnant women was 6.90±3.68 and that of non-pregnant women was 4.46±3.73; there was a basic qualification in mean metaphase II oocyte check among pregnant and non-pregnant women (P = 0.016); being higher in pregnant women. The mean abnormal oocyte count of all women was 0.63±1.26, that of pregnant women was 0.28±0.45 and that of non-pregnant women was 1.00±1.68. Oxidative stress markers inside and out affected clinical pregnancy result (P < 0.05) and appear to impact clinical pregnancy bring about women undergoing ICSI due to its effect of oocyte characteristics.