This study aimed to estimate the effect of cobalt nanoparticles (Co NPs) with different concentrations against multidrug-resistant (MDR) pathogenic bacteria. Three isolates of (gram-positive), . (gram-negative), and (gram-negative) bacteria were extracted from various clinical examples utilizing routine methods on bacteriological culture media. The antibacterial sensitivity of commercial antibiotics such as Ciprofloxacin, Cefotaxime, Gentamycin, and Amoxicillin was broken down on a Muller Hinton agar plate and evaluated using the disk diffusion method. The study results demonstrated the antibacterial effect of the Co NPs against the bacterial isolates with three different concentrations utilized in the study. The results indicated that the Co NPs showed the highest antibacterial activity when utilizing 100 μg/ml against followed by and with zones of inhibition measured as 22.2±0.1 mm, 20.3±0.15 mm, and 15.8±0.1 mm; respectively. Co NPs at a 100 μg/mL concentration showed higher inhibition zones than several common antibiotics except for Ciprofloxacin, which demonstrated better antibacterial activity against the bacterial isolates employed in this study. Scanning Electron Microscope (SEM)and X-Ray diffraction (XRD)studies confirmed that Cobalt nanoparticles (Co NPs) were synthesized from cobalt sulphate solution with a size ranging from 40 nm to 60 nm. The nanoparticles showed a crystalline structure with a round shape and smooth surface. The antibacterial resistance of Co NPs against three common bacteria such as , , and was assessed in this study. The optimum concentration of the Co NPs was identified as 100 μg/ml, which could provide a similar or higher antibacterial effect.
Problem: The commonly used acrylic resins for fabricating denture base suffer from poor mechanical properties. Aim: This study aimed to assess the effect of incorporating Titanium Dioxide (TiO2) nanoparticles (NPs) as a reinforcement agent on the compressive strength of different acrylic denture base materials. Materials and methods: Thirty-two cylindrical specimens (22 mm in height and 12 mm in diameter) were prepared from PMMA resins with and without TiO2 NPs. They were allocated into two main groups according to the materials used such as cold cure and heat cure denture base resins and then divided into two subgroups each containing eight specimens: control (without nanoparticles) and experimental (with 2 wt.% TiO2 NPs). TiO2 NPs were synthesized via a chemical processing route. Particle morphology and size distribution were assessed using SEM and AFM while XRD technique was employed to determine the crystalline structure of the NPs. Compression test was performed on the specimens using a universal Instron testing machine to compare the compressive strength. Results: Size of crystalline TiO2 NPs varied between 40-80 nm. The mean compressive strength for the cold cure acrylic resin (control group) and its nanocomposite (experimental group) were found to be 15.37 MPa and 17.42 MPa while for the heat cure acrylic resin and its nanocomposite were 23.04 MPa and 24.30 MPa. A statistically significant difference was recorded between the compressive strengths of cold cure acrylic resin and its nanocomposite. However, the difference was non-significant in the case of heat cure acrylic resin. Conclusion: The compressive strengths of both cold cure and heat cure acrylic resins increased after the incorporation TiO2 NPs.
More recently aluminum doped zinc oxide (ZnO:Al) thin films have attracted a lot of attention as an alternative to indium tin oxide (ITO) for optoelectronic devices in order to produce energy such as solar cells. In this work, ZnO:Al thin films were deposited onto quartz and silicon substrates by RF magnetron sputtering technique and the effect of Al doping on structural, optical and sensing properties of the films were studied. The dopant concentration was varied between 1 wt.% and 3 wt.% in the thin films. The crystalline structure of the films were investigated by X-ray diffraction, which indicated wurtzite structure along (100) plane. The surface morphology of the films characterized by AFM revealed that the grain size decreased with increasing dopant concentration.The films also exhibited changes in optical properties due to a decrease in band gap with increasing Al concentration. Hall measurement confirmed that the ZnO films exhibited an n-type conductivity. The results of gas sensing experiments showed that the sensitivity of the ZnO films for detecting CO2 enhanced with an increase in dopant concentration.
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