Data on the prevalence of non-amblyopic anisometropia amongst adults throughout the world were tabulated and plotted as a function of age. The global picture reveals a systematic rise in the prevalence of anisometropia with age, the fitted linear regression having a significant positive slope of 1% (p < 0.0005) for every 7 years. The distribution may embrace a juvenile rise and a later, post-presbyopic one, perhaps due to neuro-senescence.

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An examination is made of possible relations between ocular morphology and refraction in man. Special attention is paid to astigmatism, prematurity, the eye at birth, and differences as between the eyes of men and women respectively. Some functional correlates are also pointed out.