Background/Aim: Recently, an increase in the number of asymptomatic rare benign liver tumors (BLTs) has been reported during health check-ups. It is difficult to determine the nature of partial rare BLTs and not easy to distinguish from malignant liver tumors. This study aimed to analysis clinical features, diagnosis, and treatment of rare BLTs to reduce misdiagnosis and provide reference for clinical practice.Methods: From January 2012 to January 2021, we treated 112 rare BLTs by hepatectomy, including 54 focal nodular hyperplasia, 14 hepatocellular adenoma, 28 hepatic angiomyolipoma, 3 hepatic granuloma, 2 inflammatory pseudotumor of the liver, 2 nodular regenerative hyperplasia, 2 hepatic lipoma, 1 solitary fibrous tumor of the liver, 1 hepatic schwannoma and 1 hepatic myelolipoma.Results: The majority of patients were middle-aged female and asymptomatic. Single tumors were dominant. The diagnostic accuracies of computed tomography (CT) and magnetic resonance imaging (MRI) were 32.5% and 44.2%, respectively. The majority of tumors were likely to be misdiagnosed as hepatocellular carcinoma (HCC) or difficult to distinguish from HCC. All patients underwent surgical treatment. Postoperative pathological and immunohistochemical examination can confirm the diagnosis. No patients without tumor recurrence or metastasis during follow up period.Conclusion: Altogether, the clinical symptoms of rare BLTs lack specificity, and their preoperative diagnosis largely depends on imaging examination, with a low diagnostic accuracy rate and high chances of misdiagnosis as HCC. Diagnosis is confirmed by pathological and immunohistochemical examination. Surgical resection for rare BLT is safe and effective, regular postoperative follow-up is necessary.

Background：Undifferentiated early gastric cancer in different patients can show a completely different type of biological behavior. The purpose of this study was to clarify the effect of a Helicobacter pylori infection in the gastric mucosa on the biological behavior of undifferentiated early gastric cancer and to provide ideas for the selection of treatment and the control of its occurrence and development.Methods: According to the inclusion and exclusion criteria, patients suspected of undifferentiated early gastric cancer who underwent gastroscopy in several hospitals in Guangxi from 2018 to 2020 were included in succession.Results: A total of 61 cases of undifferentiated early gastric cancer, 41 cases of H. pylori from the related gastric cancer group (including 16 cases of H. pylori infection and 25 cases of previous infection), 20 cases from the H. pylori negative group (control group). The neutrophil lymphocyte ratio, lymph node metastasis rate, and the glucocholesterol glycoside from the H. pylori related gastric cancer group were higher than those from the control group.Conclusion: H. pylori can inhibit T cell immunity through the glucocholesterol glycoside and promote the development and metastasis of undifferentiated early gastric cancer.

Background and objectives Breast cancer is one of the most common malignant tumors in women. Herein, we compared the analgesic efficacy of ultrasound-guided rhomboid intercostal nerve block , erector spinae plane block and serratus plane block after modified radical mastectomy of unilateral breast cancer. Methods: A total of 90 patients who underwent modified radical mastectomy for unilateral breast cancer were selected. patients were randomly allocated into three groups receiving ultrasound-guided serratus plane block, erector spinae plane block, and the rhomboid intercostal block group. All groups received 20 mL 0.5% ropivacaine. Within 24 hours after operation, the patient received intravenous injection of tramadol 1-2 mg/kg to relieve pain in the surgical ward. Results: The dosage of tramadol 24-hours postoperatively in the rhomboid intercostal block and erector spinae plane block groups was significantly lower than that in serratus plane block group (P < 0.001). There was no statistical difference in tramadol consumption between the erector spinae plane block and rhomboid intercostal block groups within 24 hours (P = 0.676). The numerical rating scale scores in the erector spinae plane block and rhomboid intercostal block groups at 0.5, 1, 3, 6, 12, 18, and 24 hours postoperatively once patients were active were significantly lower than in the serratus plane block group (P < 0.05 for all comparisons); however, The numerical rating scale scores between rhomboid intercostal block and erector spinae plane block groups did not differ significatively within 24 hours after surgery when patients were active. Conclusions: Ultrasound-guided rhomboid intercostal block and erector spinae plane block can reduce the dosage of tramadol and NRS score compared with serratus plane block after modified radical mastectomy.

Background Undifferentiated early gastric cancer in different patients can show a completely different type of biological behavior. The purpose of this study was to clarify the effect of Helicobacter pylori infection in the gastric mucosa on the biological behavior of undifferentiated early gastric cancer and to provide ideas for the selection of treatment and the control of its occurrence and development. Methods According to the inclusion and exclusion criteria, patients suspected of undifferentiated early gastric cancer who underwent gastroscopy in several hospitals in Guangxi from 2018 to 2020 were included in succession. Results A total of 61 cases of undifferentiated early gastric cancer, 41 cases from the H. pylori related gastric cancer group (including 16 cases of H. pylori infection and 25 cases of previous infection), 20 cases from the H. pylori negative group (control group). The neutrophil lymphocyte ratio, lymph node metastasis rate, and the glucocholesterol glycoside from the H. pylori related gastric cancer group were higher than those from the control group. Conclusion H. pylori can inhibit T cell immunity through the glucocholesterol glycoside and promote the development and metastasis of undifferentiated early gastric cancer.