Commonly, phased array antennas are used to provide spatial resolution for direction of arrival (DOA) estimations. However, the phase‐array‐based DOA estimations usually require complicated system architecture and signal processing. Digital programmable metasurfaces (DPMs) can realize flexible spatial modulations of electromagnetic (EM) waves without using massive transceivers, and hence can be used for DOA estimations with much simplified architectures. Here, a mechanism of DPM‐based DOA estimations at Ka band is proposed. A reflective DPM is designed to produce a series of dual beams in random, so as to establish a sensing matrix and sample the incident wave. Orthogonal matched pursuit algorithm is used to estimate DOA from the sparsely sampled datasets. The performances of the DPM‐based DOA estimations are demonstrated by simulations and experiments for the cases of single source and double sources. This work promotes the development of DPMs and is expected to find important applications in radar and wireless communication systems, as well as the joint radar and communication systems.
The molecular functions of betanodavirus non-structural protein B and its role in host cell survival remain unclear. In the present study, we examined the roles of specific nuclear targeting domains in B1 localization as well as the effect of B1 nuclear localization on the cell cycle and host cell survival. The B1 protein of the Red spotted grouper nervous necrosis virus (RGNNV) was detected in GF-1 grouper cells as early as 24 hours post-infection (hpi). Using an EYFP-B1 fusion construct, we observed nuclear localization of the B1 protein (up to 99%) in GF-1 cells at 48 hpi. The nuclear localization of B1 was mediated by two arginine-rich nuclear targeting domains (B domain: 46RRSRR51; C domain: 63RDKRPRR70) and domain C was more important than domain B in this process. B1 nuclear localization correlated with upregulation of p53 and p21(wef1/cip1); downregulation of Cyclin D1, CDK4 and Mdm2; and G1/S cell cycle arrest in GF-1 cells. In conclusion, nuclear targeting of the RGNNV B1 protein via two targeting domains causes cell cycle arrest by up-regulating p53/p21 and down-regulating Mdm2, thereby regulating host cell survival.
Digital coding metasurfaces composed of subwavelength meta-atoms can flexibly control electromagnetic waves to achieve holography, which has great potential in millimeter-wave imaging systems and data storage. In this paper, we propose a 3-bit reflective digital coding metasurface. The incident linearly polarized waves can be transformed into cross-polarized components with distinct phase responses by adjusting the rotational and open angles of the coding elements. The 3-bit phase performance can be retained over a wide bandwidth from 12 to 18 GHz by simultaneously changing the rotational and open angles. Based on the proposed broadband metasurface, broadband holography is successfully demonstrated with the optimization of a modified Gerchberg–Saxton algorithm. As a proof of concept, five schemes with different holograms integrating the letters “S,” “E,” “U,” “X,” and “Z” are simulated from 12 to 18 GHz. Good simulation results validate the performance of the proposed broadband holography, showing a relative bandwidth of 40%. Two prototypes superposing the holograms of letters “U” and “X” are fabricated and measured in a near-field microwave anechoic chamber. The experimental results corroborate well with simulated results, further supporting the demonstration. We believe that the proposed broadband holography based on the digital coding metasurface paves a way to wideband applications for microwave imaging, information processing, and holographic data storage.
The publications on elbow pain (EP) in overhead sports are increasing. The results of previous studies mostly focus on the influence of EP in the ball game and throwing sports. Thus, a bibliometric analysis of these publications may show the direction of hot topics and future research trends. The purpose of this study is to identify the research trends on EP in overhead sports. For the methods, the first step is to use the main keywords of ‘Elbow pain’ and ‘Overhead sport’ merging auxiliary vocabulary to reach the relevant global publications between 1970 and 2022 in the Web of Science (WoS) database. The literature data set is imported into EndNote literature manager software to remove duplication. Secondly, the duplication-reduced articles are imported to an Excel sheet according to the inclusion and exclusion criteria of this study. In the third step, VOSviewer software is applied as the main analysis tool in extracting data for analysis from the articles. Then, the main research results for three aspects are obtained by VOSviewer software which extracted and analyzed the parameters of author name, article title, publication journal, keywords, organization, publication country/region, and the sum of times cited from 455 qualified papers. The study found that the United States of America made the most outstanding contribution to this theme study. The research on EP in overhead sports in China requires more attention from scholars. EP in swimming is a new research direction worthy of attention. In conclusion, the research results prove the growth trend of EP in overhead sports. The EP problem not only exists in the ball game and throwing sports but also swimming. Sport commercialization and the involvement of related professional sports organizations determine the degree of EP’s attention in a specific sport and the development of solutions. The development of a region or country also affects the depth and scope of EP study. Clinical research development and in-depth exploration are one of the bases to solve EP problems. Non-clinical action is beneficial to EP patients, but it still needs to be explored and studied.
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