European Union's Horizon 2020 program Marie Skłodowska-Curie (764920) for funding. We are grateful to the industrial affiliates of the Centre of Excellence for Biocatalysis (CoEBio3) for a studentship to T.M. Scheme 6. AaeUPO-catalyzed hydroxylation of 15 using Au-TiO 2 .Scheme 7. Aryl iodide and sulfinic acid salt cross-coupling model reaction used for reaction optimization.

A platform has been developed to enable standardization of light sources, allowing consistent scale‐up from high‐throughput screening in batch to flow, using the same pseudo‐monochromatic light source. The impact of wavelength and light intensity on a photochemical reaction was evaluated within this platform using the Wohl‐Ziegler benzylic bromination of 4‐methyl‐3‐(trifluoromethyl)benzonitrile with N‐bromosuccinimide as a model system. It was found that only 40 % of the maximum light intensity was required while still maintaining reaction rate, allowing more reliable temperature control and lower energy consumption. The optimized reaction conditions were subsequently applied to a range of synthetically relevant (hetero)aromatic compounds under continuous conditions, exploring the scope of the process within a mild and scalable procedure.