The conventional approaches for treating bone defects such as autografts donor tissue shortages and allografts transmission of diseases pose many shortcomings. The objective of this study was to design a nano strontium/magnesium doped hydroxyapatite (Sr/Mg-HA) with chitosan (CTS) and multi-walled carbon nanotubes (MWCNT) (Sr/Mg-HA/MWCNT/CTS) biocomposite was created to support the growth of osteoblasts using a solvent evaporation method. To help the growth of osteoblasts, a solvent evaporation technique was used to design a nano strontium/magnesium doped hydroxyapatite with chitosan and multi-walled carbon nanotubes biocomposite. We studied the biocompatibility and efficiency in vitro of biocomposite following physicochemical analyzes. Tests of biocompatibility, cell proliferation, mineralization, and osteogenic differentiation have shown that in-vitro safety and effectiveness of biocomposite are good. The performance of biocomposite was more efficient in in-vitro as well as in vivo experiments than in Sr/Mg-HA nanoparticles. Briefly, the Sr/Mg-HA/MWCNT/CTS biocomposite is an ideal candidate for effective bone repair in clinics with excellent mechanical properties with durable multi-biofunctional antibacterial properties and osteoinductivity.
PSOD process has serious hysteresis phenomenon and belongs to the large hysteresis system. On the basis of analyzing the working mechanism of the system, the PID control, Smith predictive control and fuzzy control are combined to control the system. Simulation results show that the proposed method has better dynamic performance than the traditional PID control method, regardless of the given input or interference. The conclusion is valuable for the safe operation and control of time-delay systems.
The panel data analysis for labour productivity convergence across provinces and sectors in China shows existence of unconditional and conditional convergence among them. While the human capital is found to have positive and significant effects on growth rates of sector-wise productivities, the FDI had positive and significant effects on growth rates of productivity across provinces. According to quantile regression, the convergence are asymmetric among provinces and sectors. The policy implications of this analysis is that low productivity sectors should improve human capital and reduce concentration for growing faster. Similarly provinces with low productivity could encourage more FDI to complement domestic investment for achieving higher rates of growth in labour productivity. This study also finds that greater inequality lowers the rate of labour productivity and hence causes more divergence across provinces. Effects income inequality on productivity are asymmetric and heterogeneous by quantiles and hence demand for an egalitarian redistribution system.
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