Our study demonstrated that young age and perforated appendicitis can affect postoperative IAA and PBO. LA appeared beneficial in reducing the length of hospitalization and postoperative IAA, but had an increasing risk of PBO. Although laparoscopic approach for pediatric appendectomy is increasing in our country, the different hospital levels and pediatric surgeon's laparoscopic experience must be evaluated in further study.
Recent advancement in microarray technologies has led to a collection of an enormous number of genetic markers in disease association studies, and yet scientists are interested in selecting a smaller set of genes to explore the relation between genes and disease. Current approaches either adopt a single marker test which ignores the possible interaction among genes or consider a multistage procedure that reduces the large size of genes before evaluation of the association. Among the latter, Bayesian analysis can further accommodate the correlation between genes through the specification of a multivariate prior distribution and estimate the probabilities of association through latent variables. The covariance matrix, however, depends on an unknown parameter. In this research, we suggested a reference hyperprior distribution for such uncertainty, outlined the implementation of its computation, and illustrated this fully Bayesian approach with a colon and leukemia cancer study. Comparison with other existing methods was also conducted. The classification accuracy of our proposed model is higher with a smaller set of selected genes. The results not only replicated findings in several earlier studies, but also provided the strength of association with posterior probabilities.
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