Isolated pulmonary metastases from soft tissue sarcomas (STS) occur in approximately 20% of the cases. Chemotherapy and surgical resection are the current standard treatment options for these patients. Our goal was to identify any prognostic factors for these patients as well as to estimate their long-term survival rate. We examined a series of twenty-two consecutive patients with pulmonary metastases from STS, treated in our institution from 1996 to 2006. Univariate (log-rank and Cox-regression) analysis was performed to identify any significant prognostic factor. Five-year survival rates were estimated by using Kaplan-Meier methods. Four patients (18.2%) were alive without any disease, twelve patients (54.5%) died of disease and we lost all track of six patients (27.3%). Follow-up period ranged from 7 to 75 months. Median follow-up: 14 months, median survival: 19 months. Disease-free interval (DFI) (P=0.005), number of lung nodules (P=0.04) and histology type (P=0.01) were significant prognostic factors at univariate analysis. The overall five-year survival rate was 23.1%. DFI, number of lung nodules at surgery and metastatic histology are significant prognostic factors for patients with resected pulmonary metastases from STS.
REsUMEnLos leiomiomas son los tumores benignos más frecuentes del esófago. Los síntomas más frecuentes son la disfagia y el dolor epigástrico, aunque un 50% de los pacientes permanecen asintomáticos y el tumor a veces se descubre por casualidad. Se presenta un caso de leiomioma esofágico con énfasis en el procedimiento quirúrgico por videotoracoscopia. Tradicionalmente, el tratamiento de elección es la enucleación transtorá-cica. En este estudio presentamos nuestra experiencia con un abordaje mínimamente invasivo.Palabras clave. Leiomioma esofágico. Videotoracoscopia. Cirugía vídeoasistida.
aBstRactLeiomyomas are the most common benign tumours of the oesophagus. The most frequent symptoms are dysphagia and epigastric pain, although 50% of patients remain asymptomatic and the tumour is sometimes discovered incidentally. We report a case of oesophageal leiomyoma with emphasis on the operative management by VATS. Traditionally, operative management by transthoracic enucleation is the procedure of choice. In this study we present our experience using a minimally invasive approach.
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